Receptor tyrosine kinase dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated colorectal cancer cell lines

被引:0
作者
Vitiello, P. P. [1 ]
Cardone, C. [1 ]
Ciardiello, D. [1 ]
Barra, G. [1 ]
Matrone, N. [1 ]
Belli, V. [1 ]
Martini, G. [2 ]
Poliero, L. [1 ]
Borrelli, C. [1 ]
Terminiello, M. [1 ]
Troiani, T. [1 ]
Morgillo, F. [1 ]
Ciardiello, F. [1 ]
Martinelli, E. [1 ]
机构
[1] Univ Campania Luigi Vanvitelli, Med Precis, Naples, Italy
[2] Vall dHebron Inst Oncol VHIO, Ctr Cellex, Barcelona, Spain
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
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20
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