A case report of primary central nervous system lymphoma

被引：6

作者：

Zeng, Xu ^{[1
,3
,4
]}

Lu, Xiaofei ^{[2
]}

Li, Xinlong ^{[1
,3
,4
]}

Peng, Lilei ^{[1
,3
,4
]}

Chen, Ligang ^{[1
,3
,4
]}

机构：

[1] Southwest Med Univ, Affiliated Hosp, Dept Neurosurg, Luzhou 646000, Peoples R China

[2] Southwest Med Univ, Affiliated Hosp, Dept Radiol, Luzhou, Peoples R China

[3] Neurosurg Clin Med Res Ctr Sichuan Prov, Wuhan, Peoples R China

[4] Academician Expert Workstn Sichuan Prov, Ziyang, Peoples R China

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2020年 / 48卷 / 07期

关键词：

Primary central nervous system lymphoma; case report; diagnosis; immune dysfunction; imaging; positron-emission tomography computed tomography; corticosteroids; stereotactic biopsy;

D O I：

10.1177/0300060520937839

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Most patients with primary central system lymphoma (PCNSL) have immune dysfunction. PCNSL without immune dysfunction is rare and extremely challenging to diagnose. Here, we report the case of a 52-year-old woman without immune dysfunction who presented with PCNSL. The patient died a few months after diagnosis and during treatment. A review of this PCNSL patient's case highlighted that poor interpretation of imaging features and the poor correlation of laboratory test results with clinical findings led to a difficulty in making a diagnosis and administering the best treatment. For an accurate diagnosis of early stage PCNSL, positron-emission tomography computed tomography and corticosteroids should be used cautiously before stereotactic biopsy.

引用

页数：5

共 7 条

[1] Lymphomatous involvement of the central nervous system [J].

Bathla, G. ;

Hegde, A. .

CLINICAL RADIOLOGY, 2016, 71 (06) :602-609

[2] Guidelines for the diagnosis and management of primary central nervous system diffuse large B-cell lymphoma [J].

Fox, Christopher P. ;

Phillips, Elizabeth H. ;

Smith, Jeffery ;

Linton, Kim ;

Gallop-Evans, Eve ;

Hemmaway, Claire ;

Auer, Dorothee P. ;

Fuller, Charlotte ;

Davies, Andrew J. ;

McKay, Pamela ;

Cwynarski, Kate ;

Jones, Gail ;

Pratt, Guy ;

Stern, Simon ;

Lambert, Jonathan ;

Parry-Jones, Nilima ;

McKay, Pam ;

Whiteway, Alastair .

BRITISH JOURNAL OF HAEMATOLOGY, 2019, 184 (03) :348-363

[3] Lymphomatosis cerebri: a rare form of primary central nervous system lymphoma. Analysis of 7 cases and systematic review of the literature [J].

Izquierdo, Cristina ;

Velasco, Roser ;

Vidal, Noemi ;

Jose Sanchez, Juan ;

Argyriou, Andreas A. ;

Besora, Sarah ;

Graus, Francesc ;

Bruna, Jordi .

NEURO-ONCOLOGY, 2016, 18 (05) :707-715

[4]

Jaffe ES., 2008, WHO CLASSIFICATION T

[5]

Lewerenz Jan, 2009, BMJ Case Rep, V2009, DOI 10.1136/bcr.08.2008.0752

[6]

Ostrom QT, 2015, NEURO-ONCOLOGY, V16, P1, DOI [10.1093/neuonc/nou327, 10.1093/neuonc/nov189, 10.1093/neuonc/nou223, 10.1093/neuonc/nox158]

[7] Primary central nervous system lymphoma in immunocompetent patients: A retrospective review of MRI features [J].

Sutherland, Tom ;

Yap, Kelvin ;

Liew, Elaine ;

Tartaglia, Con ;

Pang, Mai ;

Trost, Nicholas .

JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 2012, 56 (03) :295-301

← 1 →