Multi-arterial infusion chemotherapy for non-small cell lung carcinoma - Significance of detecting feeding arteries and tumor staining

被引：36

作者：

Nakanishi, Masanori ^{[1
]}

Demura, Yoshiki ^{[1
]}

Umeda, Yukihiro ^{[1
]}

Mizuno, Shiro ^{[1
]}

Ameshima, Shingo ^{[1
]}

Chiba, Yukio ^{[1
]}

Ishizaki, Takeshi ^{[1
]}

机构：

[1] Fukui Hosp, Natl Hosp Org, Dept Thorac Surg, Fukui, Japan

来源：

LUNG CANCER | 2008年 / 61卷 / 02期

关键词：

lung cancer; arterial infusion; chemotherapy; bronchial arterial; infusion; angiography; tumor staining; feeding artery; lymph node; metastasis;

D O I：

10.1016/j.lungcan.2007.12.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The present study examines the significance of defining feeding arteries to arterial infusion chemotherapy for patients with non-small cell lung carcinoma. We retrospectively studied feeding arteries and findings from 32 patients treated by arterial infusion chemotherapy. We graded tumor staining by angiography and compared grade in the bronchial artery with that of total staining in all detected feeding arteries, and investigated the relationship between grade and treatment response. One patient achieved a complete response and 16 achieved a partial response with no serious adverse effects. Many feeding arteries were detected and the grade of total tumor staining in these patients was significantly higher than that of tumor staining in the bronchial artery. The number of lesions that responded was significantly increased among those with a higher grade of total tumor staining. Precise definition of feeding arteries and sufficient tumor staining are vital to ensure a successful outcome of arterial infusion chemotherapy for patients with NSCLC. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：227 / 234

页数：8

共 16 条

[1]

CAULDWELL EW, 1984, SURG GYNECOL OBSTET, V86, P359

[2] BRONCHIAL ARTERY INFUSION OF MITOMYCIN-C IN CARCINOMA OF THE LUNG [J].

EKHOLM, S ;

ALBRECHTSSON, U ;

TYLEN, U .

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 1983, 6 (02) :86-96

[3]

Fujiyoshi F, 1992, J JPN RADIOL SOC, V52, P928

[4] DOUBLE BLOOD-SUPPLY OF BRONCHOGENIC-CARCINOMA FROM MULTIPLE ARTERIES [J].

HELLEKANT, C ;

JONSSON, K .

ACTA RADIOLOGICA-DIAGNOSIS, 1981, 22 (04) :403-406

[5] BRONCHIAL ARTERY INFUSION OF MITOMYCIN-C IN ADVANCED BRONCHOGENIC CARCINOMA [J].

HELLEKANT, C ;

SVANBERG, L .

ACTA RADIOLOGICA ONCOLOGY, 1978, 17 (06) :449-462

[6] SELECTIVE BRONCHIAL ARTERIOGRAPHY AND INTRA-ARTERIAL CHEMOTHERAPY IN CARCINOMA OF LUNG [J].

KAHN, PC ;

PAUL, RE ;

RHEINLANDER, HF .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1965, 50 (05) :640-+

[7]

KOSHIISHI H, 2000, JPN J CANC CHEMOTHER, V27, P1907

[8]

NAKAMURA Y, 1986, JPA J CANC CHEMOTHER, V13, P3436

[9] Effective use of multi-arterial infusion chemotherapy for advanced non-small cell lung cancer patients: Four clinical specified cases [J].

Nakanishi, Masanori ;

Umeda, Yukihiro ;

Demura, Yoshiki ;

Ameshima, Shingo ;

Chiba, Yukio ;

Miyamori, Isamu ;

Ishizaki, Takeshi .

LUNG CANCER, 2007, 55 (02) :241-247

[10]

NEYAZAKI T, 1969, CANCER-AM CANCER SOC, V24, P912

← 1 2 →