Synthesis of stable isotope labeled 3-acetyldeoxynivalenol

被引：12

作者：

Bretz, M ^{[1
]}

Beyer, M ^{[1
]}

Cramer, B ^{[1
]}

Humpf, HU ^{[1
]}

机构：

[1] Univ Munster, Inst Lebensmittelchem, D-48149 Munster, Germany

来源：

MOLECULAR NUTRITION & FOOD RESEARCH | 2005年 / 49卷 / 12期

关键词：

acetyldeoxynivalenol; analysis; deoxynivalenol; stable isotope; synthesis; trichothecenes;

D O I：

10.1002/mnfr.200500153

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Stable isotope labeled 3-acetyldeoxynivalenol (3-AcDON) was synthesized in excellent yield from deoxynivalenol as starting material. This is the first synthesis of a stable isotope labeled type-B trichothecene suitable as internal standard for HPLC-MS/MS or GC-MS analysis of trichothecene mycotoxins. The isotopic purity of the 3-d(3)-AcDON was determined to be 94.9%.

引用

页码：1151 / 1153

页数：3

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