Laser Ablation of Newly Diagnosed Malignant Gliomas: a Meta-Analysis

被引:48
作者
Ivan, Michael E. [1 ]
Mohammadi, Alireza M. [2 ]
De Deugd, Nicoleta [1 ]
Reyes, Joshua [1 ]
Rodriguez, Gregor [1 ]
Shah, Ashish [1 ]
Barnett, Gene H. [2 ]
Komotar, Ricardo J. [1 ]
机构
[1] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Dept Neurol Surg, Miami, FL 33136 USA
[2] Cleveland Clin, Neurol & Taussig Canc Inst, Dept Neurol Surg, Rose Ella Burkhardt Brain Tumor & Neurooncol Ctr, Cleveland, OH 44106 USA
关键词
Brain tumors; Laser-interstitial thermotherapy; Glioblastoma; Glioma; Minimally invasive neurosurgery; INTERSTITIAL THERMAL THERAPY; RECURSIVE PARTITIONING ANALYSIS; GLIOBLASTOMA PATIENTS; PROGNOSTIC-FACTORS; RECURRENT GLIOBLASTOMAS; BRAIN; MRI; SURVIVAL; RESECTION; THERMOTHERAPY;
D O I
10.1227/NEU.0000000000001446
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: Magnetic resonance-guided laser-interstitial thermotherapy (MR-LITT) is a minimally invasive technique that shows promise in neuro-oncology because of its superiority in delivering precise minimally invasive thermal energy with minimal collateral damage. OBJECTIVE: In this analysis, we investigate initial data on the use of MR-LITT in the treatment of newly diagnosed high-grade gliomas. METHODS: With the use of the PubMed, OVID, and Google-scholar database systems, a comprehensive search of the English literature was performed. Eighty-five articles were identified plus 1 that is pending publication. Four articles were accounted for in this review, including 25 patients with newly diagnosed high-grade gliomas who underwent MR-LITT treatment. We evaluated safety, progression-free survival, and overall survival. RESULTS: Twenty-five patients with a mean age of 53.8 years underwent LITT treatments. On average, 82.9% of the pretreatment lesion volume was ablated. The average tumor volume treated was 16.5 cm(3). The mean follow-up time was 7.6 months. Median overall survival was found to be 14.2 months (range 0.1-23 months). The median progression-free survival was 5.1 months (range 2.4-23 months); however, these data are limited by the relatively short follow-up of the patients reviewed and small sample size of only 25 patients. There was 1 (3.4%) major perioperative complication, which was a central nervous system infection. CONCLUSION: MR-LITT is a promising technology for the treatment of small, yet difficult-to-treat newly diagnosed high-grade gliomas. This study demonstrates that MR-LITT is safe, and future randomized studies are needed to evaluate its role as a treatment adjunct for newly diagnosed high-grade gliomas.
引用
收藏
页码:S17 / S23
页数:7
相关论文
共 35 条
[1]  
Ascher P W, 1991, Acta Neurochir Suppl (Wien), V52, P78
[2]   The role of magnetic resonance-guided laser ablation in neurooncology [J].
Banerjee, Christopher ;
Snelling, Brian ;
Berger, Michael H. ;
Shah, Ashish ;
Ivan, Michael E. ;
Komotar, Ricardo J. .
BRITISH JOURNAL OF NEUROSURGERY, 2015, 29 (02) :192-196
[3]  
BARNARD RO, 1987, CANCER-AM CANCER SOC, V60, P1519, DOI 10.1002/1097-0142(19871001)60:7<1519::AID-CNCR2820600719>3.0.CO
[4]  
2-1
[5]  
Bettag M, 1991, Acta Neurochir Suppl (Wien), V52, P81
[6]   MR-guided laser-induced thermal therapy (LITT) for recurrent glioblastomas [J].
Carpentier, Alexandre ;
Chauvet, Dorian ;
Reina, Vincent ;
Beccaria, Kevin ;
Leclerq, Delphine ;
McNichols, Roger J. ;
Gowda, Ashok ;
Cornu, Philippe ;
Delattre, Jean-Yves .
LASERS IN SURGERY AND MEDICINE, 2012, 44 (05) :361-368
[7]   Laser thermal therapy: Real-time MRI-guided and computer-controlled procedures for metastatic brain tumors [J].
Carpentier, Alexandre ;
McNichols, Roger J. ;
Stafford, R. Jason ;
Guichard, Jean-Pierre ;
Reizine, Daniel ;
Delaloge, Suzette ;
Vicaut, Eric ;
Payen, Didier ;
Gowda, Ashok ;
George, Bernard .
LASERS IN SURGERY AND MEDICINE, 2011, 43 (10) :943-950
[8]   Magnetic Resonance Imaging-Guided Focused Laser Interstitial Thermal Therapy for Intracranial Lesions: Single-Institution Series [J].
Hawasli, Ammar H. ;
Bagade, Swapnil ;
Shimony, Joshua S. ;
Miller-Thomas, Michelle ;
Leuthardt, Eric C. .
NEUROSURGERY, 2013, 73 (06) :1007-1017
[9]   MGMT gene silencing and benefit from temozolomide in glioblastoma [J].
Hegi, ME ;
Diserens, A ;
Gorlia, T ;
Hamou, M ;
de Tribolet, N ;
Weller, M ;
Kros, JM ;
Hainfellner, JA ;
Mason, W ;
Mariani, L ;
Bromberg, JEC ;
Hau, P ;
Mirimanoff, RO ;
Cairncross, JG ;
Janzer, RC ;
Stupp, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (10) :997-1003
[10]   Magnetic Resonance Thermometry-Guided Laser-Induced Thermal Therapy for Intracranial Neoplasms: Initial Experience [J].
Jethwa, Pinakin R. ;
Barrese, James C. ;
Gowda, Ashok ;
Shetty, Anil ;
Danish, Shabbar F. .
NEUROSURGERY, 2012, 71 :133-144