The utilization of twelve-lead electrocardiography for predicting sudden cardiac death after heart transplantation

被引：9

作者：

Chang, Hung-Yu ^{[1
,3
,4
]}

Yin, Wei-Hsian ^{[1
,5
]}

Lo, Li-Wei ^{[2
,3
,4
]}

Lin, Yenn-Jiang ^{[2
,3
,4
]}

Chang, Shih-Lin ^{[2
,3
,4
]}

Hu, Yu-Feng ^{[2
,3
,4
]}

Feng, An-Ning ^{[1
,5
]}

Chiang, Meng-Cheng ^{[1
]}

Young, Mason-Shing ^{[1
]}

Chang, Chong-Yi ^{[6
]}

Chuang, Yi-Cheng ^{[6
]}

Chong, Eric ^{[2
]}

Chen, Shih-Ann ^{[2
,3
,4
]}

Wei, Jeng ^{[6
]}

机构：

[1] Cheng Hsin Gen Hosp, Div Cardiol, Taipei 112, Taiwan

[2] Taipei Vet Gen Hosp, Div Cardiol, Taipei, Taiwan

[3] Natl Yang Ming Univ, Inst Clin Med, Taipei 112, Taiwan

[4] Natl Yang Ming Univ, Cardiovasc Res Ctr, Taipei 112, Taiwan

[5] Natl Yang Ming Univ, Sch Med, Fac Med, Taipei 112, Taiwan

[6] Cheng Hsin Gen Hosp, Div Cardiovasc Surg, Taipei 112, Taiwan

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2013年 / 168卷 / 03期

关键词：

Heart transplantation; Sudden death; Electrocardiography; Heart rate; CORONARY-ARTERY-DISEASE; QRS DURATION; INTERNATIONAL SOCIETY; UNEXPECTED DEATH; PROGNOSTIC VALUE; QTC INTERVAL; RISK; RECIPIENTS; MORTALITY; POPULATION;

D O I：

10.1016/j.ijcard.2013.03.029

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Sudden cardiac death (SCD) occurs commonly after heart transplantation (HTX). The utilization of surface electrocardiography (ECG) to assess post-HTX SCD has not been investigated thoroughly. This study aimed to investigate the specific changes in surface ECG in HTX patients with SCD. Methods: A total of 227 HTX patients (age 48 +/- 14 y/o, mean donor age 34 +/- 14 y/o, 173 males) were followed up regularly at the outpatient clinic. Twelve-lead ECG's were recorded during 1-2 monthly visits. Serial ECG parameters and relevant clinical data were collected and analyzed. Results: During the follow-up period of 96 +/- 51 months, SCD occurred in 28 (12.3%) patients. The baseline ECG parameters were comparable between patients with and without SCD. Important ECG trends of rising rest heart rates and prolongation of corrected QT (QTc) and JT (JTc) intervals were observed prior to development of SCD. After adjustment for other clinical variables, the independent predictors for SCD were older donor age (p = 0.014, OR 1.05, 95% CI 1.01-1.09), faster heart rate (p = 0.006, OR 1.06, 95% CI 1.02-1.1) and longer JTc interval (p = 0.015, OR 1.03, 95% CI 1.01-1.06). SCD occurred in 71.4% patients presenting with all three risk predictors. Conclusions: Besides older donor age, important ECG signs, including prolongation of the JTc interval and increased heart rate during post HTX follow up, could predict SCD. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：2665 / 2672

页数：8

共 26 条

[1] Cause of death and sudden cardiac death after heart transplantation - An autopsy study [J].