Major therapeutic advances and new perspectives in onco-hematology

被引:7
作者
Bay, Jacques-Olivier [1 ,2 ]
Guieze, Romain [1 ,2 ]
Ravinet, Aurelie [1 ]
Lemal, Richard [1 ]
Xhaard, Alienor [3 ]
Bailly, Sebastien [1 ]
Molucon-Chabrot, Cecile [1 ]
Hermet, Eric [1 ]
Biau, Julian [4 ]
Verrelle, Pierre [4 ]
de latour, Regis Peffault [3 ]
Tournilhac, Olivier [1 ,2 ]
机构
[1] CHU Clermont Ferrand, Serv Hematol Clin Adulte & Therapie Cellulaire, F-63003 Clermont Ferrand 01, France
[2] Univ Auvergne, EA7283, CIC501, F-63000 Clermont Ferrand, France
[3] Hop St Louis, Serv Hematol Greffe, F-75010 Paris, France
[4] Ctr Jean Perrin, Serv Radiotherapie, F-63000 Clermont Ferrand, France
关键词
cancer; chemotherapy; targeted therapies; allo-graft; perspective; retrospective; CHRONIC LYMPHOCYTIC-LEUKEMIA; EXTENDED-FIELD RADIOTHERAPY; BONE-MARROW-TRANSPLANTATION; STEM-CELL TRANSPLANTATION; ACUTE MYELOID-LEUKEMIA; ABL TYROSINE KINASE; HODGKINS-LYMPHOMA; COMBINATION CHEMOTHERAPY; RADIATION-THERAPY; BODY IRRADIATION;
D O I
10.1684/bdc.2013.1751
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hematology Oncology has a rich history including few crucial therapeutic innovations. These were possible because of the evolution of the cell and molecular biology allowing a better understanding of basic mechanisms of cancerogenesis. We propose here to summarize the most important therapeutic innovations since the beginning of Hematology/Oncology history. We also describe evolution of therapeutic strategies themselves. New insights and therapeutic perspectives for next future are also discussed.
引用
收藏
页码:587 / 599
页数:13
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