Body mass index and obstructive sleep apnoea in the UK: a cross-sectional study of the over-50s

被引:33
作者
Wall, Hannah [1 ]
Smith, Chris [2 ]
Hubbard, Richard [2 ]
机构
[1] NHS Improvement, Leicester LE1 6NB, Leics, England
[2] Univ Nottingham, Div Epidemiol & Publ Hlth, Nottingham NG7 2RD, England
来源
PRIMARY CARE RESPIRATORY JOURNAL | 2012年 / 21卷 / 04期
关键词
body mass index; epidemiology; primary care; sleep apnoea; IMPROVEMENT NETWORK THIN; MORBIDLY OBESE-PATIENTS; PREVALENCE; VALIDATION; DATABASE;
D O I
10.4104/pcrj.2012.00053
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: An increasing prevalence of obesity in the UK has also seen a rise in the diagnosis of co-morbidities. Obstructive sleep apnoea (OSA) has previously been associated with body mass index (BMI) but has not been fully explored in a UK population. Aims: To quantify the association between BMI and a recorded diagnosis of OSA in primary care for people aged 50 years or over in the UK. Methods: A descriptive analysis is given of men and women aged 50 or over in the UK from The Health Improvement Network (THIN) database with regard to diagnosis of OSA, snoring, and BMI. Logistic regression was performed for the likelihood of OSA depending on BMI classification recorded after adjusting for gender, age, region, and socioeconomic status (Townsend quintile). The analyses were repeated for snoring. Results: After adjusting for confounders, those with a BMI recorded of 40+ kg/m(2) were 27.39 times (95% CI 24.64 to 30.46) more likely to have OSA (p<0.0001). There was a lower prevalence of OSA with increasing age and levels of deprivation. Conclusions: Obesity and snoring were both strongly associated with a diagnosis of OSA. The decreasing prevalence of OSA with increasing age and levels of deprivation needs further study to ensure that these groups are not being systematically under-investigated. (C) 2012 Primary Care Respiratory Society UK. All rights reserved. H Wall et al. Prim Care Respir J 2012; 21(4): 371-376 http://dx.doi.org/10.4104/pcrj.2012.00053
引用
收藏
页码:371 / 376
页数:6
相关论文
共 18 条
[1]   Obstructive sleep apnea syndrome in morbid obesity - Effects of intragastric balloon [J].
Busetto, L ;
Enzi, G ;
Inelmen, EM ;
Costa, G ;
Negrin, V ;
Sergi, G ;
Vianello, A .
CHEST, 2005, 128 (02) :618-623
[2]   Prevalence and severity of sleep apnea in a group of morbidly obese patients [J].
Daltro, Carla ;
Gregorio, Paloma Baiardi ;
Alves, Erivaldo ;
Abreu, Mauricio ;
Bomfim, Daniel ;
Chicourel, Maria Helena ;
Araujo, Leila ;
Cotrim, Helma P. .
OBESITY SURGERY, 2007, 17 (06) :809-814
[3]   Complications of obesity - Obesity and obstructive sleep apnea-hypopnea syndrome [J].
de Sousa, A. G. P. ;
Cercato, C. ;
Mancini, M. C. ;
Halpern, A. .
OBESITY REVIEWS, 2008, 9 (04) :340-354
[4]   Obstructive sleep APNEA [J].
Flemons, WW .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (07) :498-504
[5]   Obstructive sleep apnoea syndrome: underestimated and undertreated [J].
Gibson, GJ .
BRITISH MEDICAL BULLETIN, 2005, 72 (01) :49-64
[6]   Validation of The Health Improvement Network (THIN) primary care database for monitoring prescriptions for smoking cessation medications [J].
Langley, Tessa E. ;
Szatkowski, Lisa ;
Gibson, Jack ;
Huang, Yue ;
McNeill, Ann ;
Coleman, Tim ;
Lewis, Sarah .
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2010, 19 (06) :586-590
[7]   Mortality risk factors in sleep apnoea: a matched case-control study [J].
Lavie, Peretz ;
Herer, Paula ;
Lavie, Lena .
JOURNAL OF SLEEP RESEARCH, 2007, 16 (01) :128-134
[8]   Validation studies of the health improvement network (THIN) database for pharmacoepidemiology research [J].
Lewis, James D. ;
Schinnar, Rita ;
Bilker, Warren B. ;
Wang, Xingmei ;
Strom, Brian L. .
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2007, 16 (04) :393-401
[9]   BMI is an independent risk factor for snoring in Chinese women aged over 30 years [J].
Li, Qing-Yun ;
Huang, Shao-Guang ;
Li, Min ;
Liu, Jia-Lin ;
Wan, Huan-Ying .
SLEEP AND BREATHING, 2009, 13 (03) :289-293
[10]  
Meal Andy, 2008, Qual Prim Care, V16, P49