Site-specific conjugation of RAFT polymers to proteins via expressed protein ligation

被引：30
|
作者：
Xia, Yan [1 ]
Tang, Shengchang [1 ]
Olsen, Bradley D. [1 ]
机构：
[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 25期
关键词：
STRATEGIES;
D O I：
10.1039/c3cc38976f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
引用
收藏
页码：2566 / 2568
页数：3
相关论文
共 50 条
  • [1] Site-Specific Conjugation of Polymers to Proteins
    Wang, Yanjing
    Wu, Chi
    BIOMACROMOLECULES, 2018, 19 (06) : 1804 - 1825
  • [2] Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation
    Takeda, S
    Tsukiji, S
    Nagamune, T
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (10) : 2407 - 2410
  • [3] Site-specific protein double labeling by expressed protein ligation: applications to repeat proteins
    De Rosa, Lucia
    Cortajarena, Aitziber L.
    Romanelli, Alessandra
    Regan, Lynne
    D'Andrea, Luca Domenico
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, 10 (02) : 273 - 280
  • [4] Site-Specific Conjugation of Bottlebrush Polymers to Therapeutic Protein via Bioorthogonal Chemistry
    Saha, Biswajit
    Lee, Jae Hun
    Kwon, Inchan
    Chung, Hoyong
    BIOMACROMOLECULES, 2024, 25 (05) : 3200 - 3211
  • [5] Regulation of protein properties via site-specific polymer conjugation
    Wang, Lei
    Li, Xin
    Wang, Hongwei
    Yuan, Lin
    Chen, Hong
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [6] Site-specific labeling of DNA-protein conjugates by means of expressed protein ligation
    Lovrinovic, Marina
    Fruk, Ljiljana
    Schroeder, Hendrik
    Niemeyer, Christof M.
    CHEMICAL COMMUNICATIONS, 2007, (04) : 353 - 355
  • [7] Site-Specific Antibody Drug Conjugates Using Streamlined Expressed Protein Ligation
    Frutos, Silvia
    Luis Hernandez, Jose
    Otero, Anabel
    Calvis, Carme
    Adan, Jaume
    Mitjans, Francesc
    Vila-Perello, Miguel
    BIOCONJUGATE CHEMISTRY, 2018, 29 (11) : 3503 - 3508
  • [8] Site-specific folate conjugation to a cytotoxic protein
    Smith, Bryan D.
    Higgin, Joshua J.
    Raines, Ronald T.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (17) : 5029 - 5032
  • [9] Site-specific protein immobilization by Staudinger ligation
    1600, American Chemical Society (125):
  • [10] Site-specific protein immobilization by Staudinger ligation
    Soellner, MB
    Dickson, KA
    Nilsson, BL
    Raines, RT
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (39) : 11790 - 11791
12345