Rituximab-induced hepatitis C virus reactivation in rheumatoid arthritis

被引：20

作者：

Lin, Ko-Ming ^{[1
,2
]}

Lin, Jing-Chi ^{[1
,2
]}

Tseng, Wen-Yi ^{[3
]}

Cheng, Tien-Tsai ^{[4
,5
,6
]}

机构：

[1] Chang Gung Mem Hosp, Div Allergy & Immunol & Rheumatol, Chiayi, Taiwan

[2] Chang Gung Univ, Coll Med, Grad Inst Clin Med Sci, Chiayi, Taiwan

[3] Chang Gung Mem Hosp, Div Allergy & Immunol & Rheumatol, Keelung, Taiwan

[4] Kaohsiung Chang Gung Mem Hosp, Div Rheumatol Allergy & Immunol, Kaohsiung, Taiwan

[5] Kaohsiung Chang Gung Mem Hosp, Dept Internal Med, Kaohsiung, Taiwan

[6] Chang Gung Univ, Coll Med, Kaohsiung, Taiwan

来源：

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | 2013年 / 46卷 / 01期

关键词：

Hepatitis C virus; Rheumatoid arthritis; Rituximab; B-CELL LYMPHOMA; MIXED CRYOGLOBULINEMIA; INFECTED PATIENTS; RECOMMENDATIONS; CHEMOTHERAPY; MULTICENTER;

D O I：

10.1016/j.jmii.2011.12.020

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The B-cell depletion agent rituximab (RTX) is used in lymphoma and rheumatoid arthritis (RA), and there have been several case reports of an RTX-induced reactivation of hepatitis C virus in patients with lymphoma. However, there have been no papers detailing hepatitis C virus reactivation after RTX therapy in a patient with RA. Here we report a case of RTX-induced hepatitis C virus reactivation in a patient with RA. Physicians should be aware that a close follow-up of liver function and viral load is mandatory after RTX therapy in patients with RA and concomitant hepatitis C. Copyright (C) 2011, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. All rights reserved.

引用

页码：65 / 67

页数：3

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