Heterogeneous catalysis with nickel-on-graphite (Ni/Cg):: Reduction of aryl tosylates and mesylates

被引：51

作者：

Lipshutz, BH ^{[1
]}

Frieman, BA ^{[1
]}

Butler, T ^{[1
]}

Kogan, V ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 05期

关键词：

aryl tosylates; graphite; heterogeneous catalysis; nickel; reduction;

D O I：

10.1002/anie.200502887

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) How would you reduce an aryl OH group? Traditionally, a palladium catalyst, a mild source of hydride, and a triflate derivative are used in solution. A more modern alternative is presented that is not only economical but heterogeneous as well. Nickel-on-graphite (Ni/C g) is introduced as a very inexpensive catalyst that reduces aryl tosylates and mesylates with excellent functional group tolerance. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：800 / 803

页数：4

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