Bacterial Outer Membrane Nanovesicles: Structure, Biogenesis, Functions, and application in Biotechnology and Medicine (Review)

被引:4
|
作者
Lusta, K. A. [1 ,2 ]
机构
[1] Russian Acad Med Sci, Human Morphol Res Inst, Moscow 117418, Russia
[2] Inst Atherosclerosis Res Skolkovo, Moscow 121609, Russia
关键词
extracellular membrane nanovesicles; bacterial outer membrane; secretion; biogenesis; interspecies communication; intercellular signals; bacterial toxins; immunity modulation; vaccine; GRAM-NEGATIVE BACTERIA; PSEUDOMONAS-AERUGINOSA PAO1; GASTRIC EPITHELIAL-CELLS; ESCHERICHIA-COLI; HELICOBACTER-PYLORI; NEISSERIA-MENINGITIDIS; VESICLE PRODUCTION; VIRULENCE FACTORS; SHIGA TOXIN; ACTINOBACILLUS-ACTINOMYCETEMCOMITANS;
D O I
10.1134/S0003683815040092
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The review summarizes the comprehensive biochemical and physicochemical characteristics of extracellular membrane nanovesicles (EMN) derived from different kinds of bacteria. The EMN structure, composition, biogenesis, secretion mechanisms, formation conditions, functions, involvement in pathogenesis, and application in biotechnology and medicine are discussed.
引用
收藏
页码:485 / 493
页数:9
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