National survey of provider opinions on controversial characteristics of liver transplant candidates

被引:52
作者
Secunda, Katharine [3 ]
Gordon, Elisa J. [2 ,3 ,4 ]
Sohn, Min W. [2 ,4 ]
Shinkunas, Laura A. [5 ]
Kaldjian, Lauris C. [5 ,6 ]
Voigt, Michael D. [7 ]
Levitsky, Josh [1 ,3 ]
机构
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Gastroenterol & Hepatol, Chicago, IL 60611 USA
[2] Northwestern Univ, Ctr Healthcare Studies, Feinberg Sch Med, Chicago, IL 60611 USA
[3] Northwestern Univ, Comprehens Transplant Ctr, Feinberg Sch Med, Chicago, IL 60611 USA
[4] Hines VA Hosp, Ctr Management Complex Chron Care, Hines, IL USA
[5] Univ Iowa, Program Bioeth & Humanities, Carver Coll Med, Iowa City, IA USA
[6] Univ Iowa, Dept Med, Carver Coll Med, Div Gen Internal Med, Iowa City, IA 52242 USA
[7] Univ Iowa, Dept Med, Carver Coll Med, Div Gastroenterol & Hepatol, Iowa City, IA 52242 USA
关键词
SOLID-ORGAN TRANSPLANTATION; HIV-INFECTED PATIENTS; LONG-TERM SURVIVAL; KIDNEY-TRANSPLANTATION; ALCOHOL-USE; PREDICTORS; RECIPIENTS; DISEASE; RELAPSE; ISSUES;
D O I
10.1002/lt.23581
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Candidate selection for liver transplantation presents challenging ethical issues that require balancing the principles of justice and utility. The goal of this study was to assess the opinions of US transplant providers regarding the ways in which controversial medical and psychosocial characteristics influence patient eligibility for liver transplantation. An online, anonymous survey about adult patient characteristics was sent to providers (hepatologists, surgeons, psychiatrists, and social workers) at all 102 active adult liver transplant centers in the United States. A majority of the providers (251/444 or 56.5%) completed the survey. The providers were queried about 8 characteristics, and the 3 that were ranked most controversial were incarceration, marijuana use, and psychiatric diagnoses. Most providers identified a patient age 80 years (62.7%), a body mass index 45 kg/m2 (56.6%), and current incarceration with a lifetime sentence (54.7%) as absolute contraindications to liver transplantation. In a multivariate analysis, the identification of absolute contraindications varied significantly with the provider type, the center volume, and the geographical region. Less than half of the providers reported that their centers had written policies regarding most of the characteristics examined. In conclusion, providers differ significantly in their opinions on controversial patient characteristics and transplant contraindications. Along with a paucity of literature data on outcomes, these provider differences may play a role in the fact that many centers do not have formal policies for selecting patients with these characteristics. Evidence-based data on the outcomes of such patients are needed to guide the formation of written policies to better standardize eligibility criteria. Liver Transpl 19:395403, 2013. (c) 2012 AASLD.
引用
收藏
页码:395 / 403
页数:9
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