Increased Allergic Sensitization to Mugwort in Chronic Urticaria

被引:10
作者
de Vos, Gabriele [1 ]
Kravvariti, Evrydiki [2 ]
Collins, Jennifer [1 ]
Tavdy, Anna [2 ]
Nazari, Ramin [1 ]
Hudes, Golda [1 ]
Rosenstreich, David [1 ]
机构
[1] Albert Einstein Coll Med, Div Allergy & Immunol, New York, NY USA
[2] Jackson Mem Med Ctr, New York, NY USA
关键词
Chronic urticaria; Mugwort; Atopy; Aeroallergen testing; AFFINITY IGE RECEPTOR; FOOD; IDENTIFICATION; PREVALENCE;
D O I
10.1159/000342356
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Mugwort pollen is known to cross-react with a variety of spices and vegetables that are typically part of elimination diets used in the treatment of chronic urticaria (CU). Objective: We sought to investigate the association between CU and allergic sensitization to mugwort pollen. Methods: We conducted 2 case-control studies comparing aeroallergen skin prick test results between patients with and without CU and with or without allergic rhinitis (total n = 202). Results: CU patients with coexisting allergic rhinitis were more than twice as likely to be sensitized to mugwort as subjects not suffering from CU (67 vs. 30%; p = 0.004). Ragweed, cat, rat and mite sensitization were also significantly associated with CU. Overall, patients with CU had more positive aeroallergen skin tests than patients without CU (p < 0.005). Conclusion: Mugwort sensitization was associated with CU, possibly contributing to beneficial effect of elimination diets. Copyright (C) 2012 S. Karger AG, Basel
引用
收藏
页码:141 / 146
页数:6
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