Preparation and Drug Release Properties of IBU-loaded Mesoporous Calcium Silicate Hydrate (CSH) spheres

被引：0

作者：

Dong, Ya ^{[1
]}

Yuan, Huiwen ^{[1
]}

Ni, Yaru ^{[1
]}

Lu, Chunhua ^{[1
]}

Xu, Zhongzi ^{[1
]}

机构：

[1] Nanjing Univ Technol, State Key Lab Mat Orient Chem Engn, Coll Mat Sci & Engn, Nanjing 210009, Peoples R China

来源：

BIOTECHNOLOGY, CHEMICAL AND MATERIALS ENGINEERING, PTS 1-3 | 2012年 / 393-395卷

关键词：

Calcium silicate hydrate; Mesoporous; drug carrier; DELIVERY SYSTEM; FABRICATION;

D O I：

10.4028/www.scientific.net/AMR.393-395.894

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The novel kind flowerlike mesoporous spheres of calcium silicate hydrate (CaO center dot SiO2 center dot H2O, CSH) have been synthesized by co-precipitation method on based with water/alcohol/calvital/ tetraethyl orthosilicate (TEOS) system. The synthesized CSH were applied as a carrier to study the loaded behaviors of ibuprofen(IBU),was used to investigate the drug loading behavior of the CSH for different times has been also discussed. The drug loading capacities(DLCs) of CSH loaded for 12h has reached 116.78wt.%. The structural, morphological and textural properties were investigated by SEM, FTIR, TG and BET. The results show that it would be a good candidate as drug carrier for bone repair.

引用

页码：894 / 897

页数：4

共 48 条

[11] Biocompatible Eu doped mesoporous calcium silicate nanospheres for pH-responsive drug release
Wang, Duo
Han, Shixing
Lu, Bing-Bing
INORGANIC CHEMISTRY COMMUNICATIONS, 2021, 133
[12] Preparation and properties of calcium aluminum silicate hydrate-polycarboxylate nanocomposites (CASH-PCE)
Zhou, Han
Liu, Bao
Lu, Duyou
Li, Dongxu
JOURNAL OF SUSTAINABLE CEMENT-BASED MATERIALS, 2024, 13 (04) : 558 - 576
[13] Preparation and drug release properties of norisoboldine-loaded chitosan microspheres
He, Miao
Wang, Haiyan
Dou, Wei
Chou, Guixin
Wei, Xiaohui
Wang, Zhengtao
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2016, 91 : 1101 - 1109
[14] Drug-Coformer Loaded-Mesoporous Silica Nanoparticles: A Review of the Preparation, Characterization, and Mechanism of Drug Release
Budiman, Arif
Wardhana, Yoga Windhu
Ainurofiq, Ahmad
Nugraha, Yuda Prasetya
Qaivani, Ridhatul
Hakim, Siti Nazila Awaliyyah Lukmanul
Aulifa, Diah Lia
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2024, 19 : 281 - 305
[15] Preparation of mesoporous calcium doped silica spheres with narrow size dispersion and their drug loading and degradation behavior
Li, Xia
Zhang, Lingxia
Dong, Xiaoping
Liang, Jian
Shi, Jianlin
MICROPOROUS AND MESOPOROUS MATERIALS, 2007, 102 (1-3) : 151 - 158
[16] Properties and drug release behavior of calcium phosphate cement loaded with two-component drug
Guo, Yuehua
Qu, Shuxin
Li, Maohong
Weng, Jie
Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society, 2010, 38 (03): : 472 - 477
[17] Preparation and in vitro Release Properties of Mercaptopurine Drug-loaded Magnetic Microspheres
Xu Haixing
Zhang Yu
Niu Xiaoqian
Wang Ling
Chen Hui
Zhang Xi
Tang Qiuhan
Huang Zhijun
Liu Hui
Xu Peihu
JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 2013, 28 (06): : 1231 - 1235
[18] Preparation and in vitro Release Properties of Mercaptopurine Drug-loaded Magnetic Microspheres
XU Haixing
ZHANG Yu
NIU Xiaoqian
WANG Ling
CHEN Hui
ZHANG Xi
TANG Qiuhan
HUANG Zhijun
LIU Hui
XU Peihu
Journal of Wuhan University of Technology(Materials Science), 2013, 28 (06) : 1231 - 1235
[19] Preparation and drug release properties of curcumin-loaded PVA/PAA nanofibers
Jiayin, Shi
Jing, Gao
Lu, Wang
Chemical Fibers International, 2022, 72 (03): : 138 - 140
[20] Preparation and in vitro release properties of mercaptopurine drug-loaded magnetic microspheres
Haixing Xu
Yu Zhang
Xiaoqian Niu
Ling Wang
Hui Chen
Xi Zhang
Qiuhan Tang
Zhijun Huang
Hui Liu
Peihu Xu
Journal of Wuhan University of Technology-Mater. Sci. Ed., 2013, 28 : 1231 - 1235

← 1 2 3 4 5 →