Lithium: a review of its metabolic adverse effects

被引：121

作者：

Livingstone, Callum ^{[1
]}

Rampes, Hagen

机构：

[1] Royal Surrey Cty Hosp, Dept Clin Biochem, Guildford, Surrey, England

[2] Barnet Enfield & Haringey Mental Hlth NHS Trust, NW Community Mental Hlth Team, Edgware, Middx, England

来源：

JOURNAL OF PSYCHOPHARMACOLOGY | 2006年 / 20卷 / 03期

关键词：

lithium; adverse effects; hypothyroidism; obesity; hyperparathyroidism; diabetes insipidus;

D O I：

10.1177/0269881105057515

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Treatment with Lithium has long been recognized to be associated with metabolic adverse effects notably hypothyroidism, hyperparathyroidism, weight gain and nephrogenic diabetes insipidus. It is important that clinicians prescribing lithium are aware of these adverse effects and have a strategy for their detection and management. We review aspects of these actions of lithium including their prevalence, risk factors, biochemical changes involved and management, and discuss some advances that have been made in their understanding in recent years.

引用

页码：347 / 355

页数：9

共 75 条

[1]

Ashrafian H, 2004, CLIN NEPHROL, V61, P440

[2] LITHIUM AND BODY-WEIGHT GAIN [J].

BAPTISTA, T ;

TENEUD, L ;

CONTRERAS, Q ;

ALASTRE, T ;

BURGUERA, JL ;

DEBURGUERA, M ;

DEBAPTISTA, E ;

WEIS, S ;

HERNANDEZ, L .

PHARMACOPSYCHIATRY, 1995, 28 (02) :35-44

[3] Endocrine effects of lithium carbonate in healthy premenopausal women:: Relationship with body weight regulation [J].

Baptista, T ;

Lacruz, A ;

De Mendoza, S ;

Guillén, MM ;

Burguera, JL ;

De Burguera, M ;

Hernández, L .

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2000, 24 (01) :1-16

[4] LITHIUM ASSOCIATED THYROTOXICOSIS - A REPORT OF 14 CASES, WITH STATISTICAL-ANALYSIS OF INCIDENCE [J].

BARCLAY, ML ;

BROWNLIE, BEW ;

TURNER, JG ;

WELLS, JE .

CLINICAL ENDOCRINOLOGY, 1994, 40 (06) :759-764

[5]

Bendz H, 1996, NEPHROL DIAL TRANSPL, V11, P457

[6] Hyperparathyroidism and long-term lithium therapy - A cross-sectional study and the effect of lithium withdrawal [J].

Bendz, H ;

Sjodin, L ;

Toss, G ;

Berglund, K .

JOURNAL OF INTERNAL MEDICINE, 1996, 240 (06) :357-365

[7] Drug-induced diabetes insipidus - Incidence, prevention and management [J].

Bendz, H ;

Aurell, M .

DRUG SAFETY, 1999, 21 (06) :449-456

[8] STABILIZATION OF MICROTUBULES BY LITHIUM ION [J].

BHATTACHARYYA, B ;

WOLFF, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 73 (02) :383-390

[9] LITHIUM STIMULATES THE RELEASE OF HUMAN PARATHYROID-HORMONE INVITRO [J].

BIRNBAUM, J ;

KLANDORF, H ;

GIULIANO, A ;

VANHERLE, A .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1988, 66 (06) :1187-1191

[10] THE COURSE OF THYROID ABNORMALITIES DURING LITHIUM TREATMENT - A 2-YEAR FOLLOW-UP-STUDY [J].

BOCCHETTA, A ;

BERNARDI, F ;

BURRAI, C ;

PEDDITZI, M ;

LOVISELLI, A ;

VELLUZZI, F ;

MARTINO, E ;

DELZOMPO, M .

ACTA PSYCHIATRICA SCANDINAVICA, 1992, 86 (01) :38-41

← 1 2 3 4 5 6 7 8 →