Apoptosis-inducing activity of ethanol extracts from the tea of mulberry (Morus alba) leaves in HL-60 cells

被引：1
|
作者：
Katsube, T [1 ]
Yamasaki, Y [1 ]
机构：
[1] Shimane Inst Ind Technol, Matsue, Shimane 6900816, Japan
来源：
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 2002年 / 49卷 / 03期
关键词：
D O I：
10.3136/nskkk.49.195
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The tea of mulberry (Morus alba) leaves were extracted with 70% ethanol. The extracts inhibited the proliferation of human promyelocytic leukemic HL-60 cells in a dose-dependent manner. The extracts activated the caspase-3 of the cells, one of the key enzyme of apoptosis. Moreover, DNA ladder formation and apoptotic body formation were observed in the presence of the extracts. These results suggest that the extracts from the tea of mulberry leaves is an excellent functional food containing effective substance for preventing cancer.
引用
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页码：195 / 198
页数：4
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