Brain Stimulation in Eating Disorders: State of the Art and Future Perspectives

被引：32

作者：

Duriez, Philibert ^{[1
,2
]}

Bou Khalil, Rami ^{[3
,4
]}

Chamoun, Yara ^{[3
]}

Maatoug, Redwan ^{[5
]}

Strumila, Robertas ^{[6
]}

Seneque, Maude ^{[4
,7
]}

Gorwood, Philip ^{[1
,2
]}

Courtet, Philippe ^{[4
,7
]}

Guillaume, Sebastien ^{[4
,7
]}

机构：

[1] St Anne Hosp, GHU Paris Psychiat & Neurosci, Clin Malad Ment & Encephale CMME, F-75014 Paris, France

[2] Univ Paris, Inst Psychiat & Neurosci Paris IPNP, INSERM, UMR S1266, 102-108 Rue Sante, F-75014 Paris, France

[3] Hotel Dieu France St Joseph Univ, Dept Psychiat, Beirut 166830, Lebanon

[4] Univ Montpellier, Neuropsychiat Epidemiol & Clin Res, INSERM, CHU Montpellier, F-34295 Montpellier, France

[5] Sorbonne Univ, Inst Cerveau, Serv Psychiat Adulte Pitie Salpetriere, AP HP,ICM, F-75013 Paris, France

[6] Vilnius Univ, Inst Clin Med, Psychiat Clin, Fac Med, LT-03101 Vilnius, Lithuania

[7] CHRU Montpellier, Dept Emergency Psychiat & Post Acute Care, F-34295 Montpellier, France

来源：

JOURNAL OF CLINICAL MEDICINE | 2020年 / 9卷 / 08期

关键词：

rTMS; deep brain stimulation; treatment; anorexia; bulimia; binge eating disorders; TRANSCRANIAL MAGNETIC STIMULATION; DORSOLATERAL PREFRONTAL CORTEX; ENDURING ANOREXIA-NERVOSA; HIGH-FREQUENCY RTMS; MEDIAL FOREBRAIN-BUNDLE; BULIMIA-NERVOSA; ELECTROCONVULSIVE-THERAPY; NUCLEUS-ACCUMBENS; DOUBLE-BLIND; SUBCALLOSAL CINGULATE;

D O I：

10.3390/jcm9082358

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The management of eating disorders (EDs) is still difficult and few treatments are effective. Recently, several studies have described the important contribution of non-invasive brain stimulation (repetitive transcranial magnetic stimulation, transcranial direct current stimulation, and electroconvulsive therapy) and invasive brain stimulation (deep brain stimulation and vagal nerve stimulation) for ED management. This review summarizes the available evidence supporting the use of brain stimulation in ED. All published studies on brain stimulation in ED as well as ongoing trials registered at clinicaltrials.gov were examined. Articles on neuromodulation research and perspective articles were also included. This analysis indicates that brain stimulation in EDs is still in its infancy. Literature data consist mainly of case reports, cases series, open studies, and only a few randomized controlled trials. Consequently, the evidence supporting the use of brain stimulation in EDs remains weak. Finally, this review discusses future directions in this research domain (e.g., sites of modulation, how to enhance neuromodulation efficacy, personalized protocols).

引用

页码：1 / 25

页数：25

共 138 条

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