Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles

被引：1

作者：

Khalifa, N. M. ^{[1
,2
]}

Al-Omar, M. A. ^{[1
]}

Ali, O. M. ^{[3
]}

机构：

[1] King Saud Univ, Dept Pharmaceut Chem, Coll Pharm, Drug Explorat & Dev Chair, Riyadh 11451, Saudi Arabia

[2] Natl Res Ctr, Pharmaceut & Drug Ind Div, Therapeut Chem Dept, Cairo 12622, Egypt

[3] Taif Univ, Fac Med & Appl Sci, Dept Chem, At Taif, Saudi Arabia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2017年 / 87卷 / 12期

关键词：

1,3,4-trisubstituted pyrazoles; 2-oxo(imino)pyridine derivatives; synthesis; PYRENE MOIETY; DERIVATIVES;

D O I：

10.1134/S1070363217120349

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.

引用

页码：2933 / 2936

页数：4

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