Synthesis of Novel 4-[1-(3-Chlorophenyl)-3-(pyren-1-yl)-1H-pyrazol-4-yl]-6-(substituted phenyl)-1,2-dihydro-2-oxo(imino)pyridine-3-carbonitriles

被引：1
|
作者：
Khalifa, N. M. [1 ,2 ]
Al-Omar, M. A. [1 ]
Ali, O. M. [3 ]
机构：
[1] King Saud Univ, Dept Pharmaceut Chem, Coll Pharm, Drug Explorat & Dev Chair, Riyadh 11451, Saudi Arabia
[2] Natl Res Ctr, Pharmaceut & Drug Ind Div, Therapeut Chem Dept, Cairo 12622, Egypt
[3] Taif Univ, Fac Med & Appl Sci, Dept Chem, At Taif, Saudi Arabia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2017年 / 87卷 / 12期
关键词：
1,3,4-trisubstituted pyrazoles; 2-oxo(imino)pyridine derivatives; synthesis; PYRENE MOIETY; DERIVATIVES;
D O I：
10.1134/S1070363217120349
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel compounds of 4,6-diaryl-2-oxo(imino)-1,2-dihydro-pyridine-3-carbonitriles has been synthesized by reaction of 1-(3-chlorophenyl)-3-(pyren-1-yl)-1H-pyrazole-4-carbaldehyde with different 1-(substituted phenyl)ethanones and ethyl cyanoacetate or malononitrile in presence of ammonium acetate. Structure of the newly synthesized compounds was elucidated from chemical and spectroscopic data.
引用
收藏
页码：2933 / 2936
页数：4
相关论文
共 50 条
  • [21] Functionalized 3-(5-aryloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(4-substituted-phenyl)prop-2-en-1-ones: synthetic pathway, and the structures of six examples
    Kumar, Haruvegowda Kiran
    Yathirajan, Hemmige S.
    Asma
    Manju, Nagaraja
    Kalluraya, Balakrishna
    Rathore, Ravindranath S.
    Glidewell, Christopher
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2020, 76 : 683 - +
  • [22] 3-Ethyl-6-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
    Fun, Hoong-Kun
    Quah, Ching Kheng
    Malladi, Shridhar
    Isloor, Arun M.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O2799 - U2456
  • [23] Synthesis and Antibacterial Evaluation of a Novel Series of 2-(1,2-Dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles
    Stella, Alessandro
    Segers, Kenneth
    De Jonghe, Steven
    Vanderhoydonck, Bart
    Rozenski, Jef
    Anne, Jozef
    Herdewijn, Piet
    CHEMISTRY & BIODIVERSITY, 2011, 8 (02) : 253 - 265
  • [24] Synthesis of (E)-(4-(Aryl)phenyl)(3-(2-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)vinyl)benzofuran-2-yl) methanones by Claisen Schmidt-Suzuki Cross Coupling and their Antibacterial and Antifungal Activity
    Ashok, Dongamanti
    Ziauddin, Mohammad
    Lakshmi, Bommidi Vijaya
    Sarasija, Madderla
    JOURNAL OF THE MEXICAN CHEMICAL SOCIETY, 2017, 61 (03) : 167 - 176
  • [25] Synthesis of some novel (1-substituted-5-phenyl-3-trifluoromethyl-1H-pyrazol-4-yl)-(substituted benzothiazol-2-yl)-diazene and their antifungal activity
    Sareen, V.
    Khatri, V.
    Shinde, D.
    Sareen, S.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2010, 87 (11) : 1415 - 1419
  • [26] Synthesis, Crystal Structure and Recognition Properties of 2-(5-(4-Chlorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl)pyridine
    Zhong Li-Qun
    Zhang Shu-Shu
    Tao Qing
    Hu Sheng-Li
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2014, 33 (05) : 779 - 784
  • [27] Design, synthesis of (Z)-3-benzyl-5-((1-phenyl-3-(3-((1-substituted phenyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-1H-pyrazol-4-yl)methylene)thiazolidine-2,4-dione analogues as potential cytotoxic agents
    Kolluri, Prashanth Kumar
    Gurrapu, Nirmala
    Edigi, Praveen Kumar
    Subhashini, N. J. P.
    Putta, Shravani
    Singh, Surya Satyanarayana
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (12) : 3244 - 3256
  • [28] (E)-3-[4-(1H-Imidazol-1-yl)phenyl]-1-(3-chloro-4-fluorophenyl)prop-2-en-1-one
    Takaki, Reina
    Ashburn, Bradley O.
    MOLBANK, 2022, 2022 (02)
  • [29] Synthesis and crystal structure of (2-chloro-4-(phenylthio)phenyl) (3-methyl-1-phenyl-5-(phenylthio)-1H-pyrazol-4-yl)methanone
    G.-X. Sun
    Z.-W. Zhai
    Z.-H. Sun
    C.-X. Tan
    J.-Q. Weng
    X.-H. Liu
    Journal of Structural Chemistry, 2017, 58 : 1663 - 1667
  • [30] 4-{3,5-Bis[2,3,5,6-tetrafluoro-4-(piperazin-1-yl)phenyl]-4,5-dihydro-1H-pyrazol-1-yl}benzaldehyde in the Synthesis of New Dendritic Chromophores
    Ishchenko, R. A.
    Orlova, N. A.
    Shelkovnikov, V. V.
    Maksimov, A. M.
    Ryazanov, N. D.
    Berezhnaya, V. N.
    Chernonosov, A. A.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2025, 61 (01) : 184 - 189
12345