Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter

被引:20
作者
Bessow, Camila [1 ,3 ]
Donato, Rafaela [1 ,3 ]
de Souza, Tatiane [3 ]
Chapon, Rita [3 ]
Genro, Vanessa [2 ,3 ]
Cunha-Filho, Joao Sabino [1 ,2 ,3 ]
机构
[1] Univ Fed Rio Grande do Sul, Rua Ramiro Barcelos 2350, Porto Alegre, RS, Brazil
[2] Hosp Clin Porto Alegre, Rua Ramiro Barcelos 2350, Porto Alegre, RS, Brazil
[3] Ctr Reprod Humana Insemine, Porto Alegre, RS, Brazil
关键词
Follicular output rate; FORT; Controlled ovarian hyperstimulation; Antral follicle size; Ovarian responsiveness; IN-VITRO FERTILIZATION; ANTI-MULLERIAN HORMONE; OVARIAN RESERVE; IVF TREATMENT; RATE FORT; NUMBER; STIMULATION; TESTS; WOMEN; MULTICENTER;
D O I
10.1186/s13048-019-0522-4
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
BackgroundThe antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: 6mm or AFC>6: >6mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries.ResultsThe mean age (SD) of the women was 36.03years (+/- 3.87years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r=-0.237, P 0.023) but not between the FORT and AFC>6 (r=-0.055, P 0.602).Conclusions The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH.
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页数:6
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