Resting-state Modulation of Alpha Rhythms by Interference with Angular Gyrus Activity

被引：39

作者：

Capotosto, Paolo ^{[1
]}

Babiloni, Claudio ^{[2
,3
]}

Romani, Gian Luca ^{[1
]}

Corbetta, Maurizio ^{[1
,4
]}

机构：

[1] Univ G DAnnunzio, I-66100 Chieti, Italy

[2] Univ Roma La Sapienza, I-00185 Rome, Italy

[3] IRCCS San Raffaele Pisana, Rome, Italy

[4] Washington Univ, Sch Med, St Louis, MO USA

来源：

JOURNAL OF COGNITIVE NEUROSCIENCE | 2014年 / 26卷 / 01期

关键词：

TRANSCRANIAL MAGNETIC STIMULATION; EPISODIC MEMORY RETRIEVAL; DEFAULT MODE NETWORK; FUNCTIONAL CONNECTIVITY; SPATIAL ATTENTION; PARIETAL CORTEX; HUMAN BRAIN; OSCILLATORY ACTIVITY; HIGH-FREQUENCY; BAND POWER;

D O I：

10.1162/jocn_a_00460

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The default mode network is active during restful wakefulness and suppressed during goal-driven behavior. We hypothesize that inhibitory interference with spontaneous ongoing, that is, not task-driven, activity in the angular gyrus (AG), one of the core regions of the default mode network, will enhance the dominant idling EEG alpha rhythms observed in the resting state. Fifteen right-handed healthy adult volunteers underwent to this study. Compared with sham stimulation, magnetic stimulation (1 Hz for 1 min) over both left and right AG, but not over FEF or intraparietal sulcus, core regions of the dorsal attention network, enhanced the dominant alpha power density (8-10 Hz) in occipitoparietal cortex. Furthermore, right AG-rTMS enhanced intrahemispheric alpha coherence (8-10 Hz). These results suggest that AG plays a causal role in the modulation of dominant low-frequency alpha rhythms in the resting-state condition.

引用

页码：107 / 119

页数：13

共 68 条

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