Lewis Acid Catalyzed SN2-Type Ring Opening of N-Activated Aziridines with Electron-Rich Arenes/Heteroarenes

被引：54

作者：

Ghorai, Manas K. ^{[1
]}

Tiwari, Deo Prakash ^{[1
]}

Jain, Nikita ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 14期

关键词：

ENANTIOSELECTIVE SYNTHESIS; MESO-AZIRIDINES; C-ARYLATION; STEREOCONTROLLED SYNTHESIS; CYCLIZATION REACTIONS; EFFICIENT CATALYST; TOSYL AZIRIDINES; SYNTHETIC ROUTE; DERIVATIVES; TRANSFORMATION;

D O I：

10.1021/jo401028j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient Lewis acid catalyzed S(N)2-type ring opening of substituted aziridines with electron-rich arenes/heteroarenes to provide substituted 2,2-diaryl/heteroarylethylamines in excellent yields and stereoselectivity (er, dr >99:1) is described.

引用

页码：7121 / 7130

页数：10

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