The risk of mortality among young children hospitalized for severe respiratory syncytial virus infection

被引：0

作者：

Szabo, Shelagh M. ^{[1
]}

Gooch, Katherine L. ^{[2
]}

Bibby, Meagan M. ^{[1
]}

Vo, Pamela G. ^{[2
]}

Mitchell, Ian ^{[3
,4
]}

Bradt, Pamela

Levy, Adrian R. ^{[1
,5
]}

机构：

[1] Oxford Outcomes, Vancouver, BC, Canada

[2] Abbott Labs, Abbott Pk, IL 60064 USA

[3] Univ Calgary, Calgary, AB, Canada

[4] Alberta Childrens Prov Gen Hosp, Calgary, AB T2T 5C7, Canada

[5] Dalhousie Univ, Dept Epidemiol & Community Hlth, Halifax, NS, Canada

来源：

PAEDIATRIC RESPIRATORY REVIEWS | 2012年 / 13卷

关键词：

Respiratory syncytial virus; Fatality; Hospitalization; Review; systematic; CONGENITAL HEART-DISEASE; INVESTIGATORS COLLABORATIVE NETWORK; RSV IMMUNE GLOBULIN; CLINICAL CHARACTERISTICS; PALIVIZUMAB PROPHYLAXIS; PRETERM INFANTS; EPIDEMIOLOGY; BURDEN; AGE; REHOSPITALIZATION;

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is the leading cause of childhood morbidity. Although also an important cause of childhood mortality worldwide, the impact of key risk factors has not been established. A systematic review of 34 articles reporting case fatality rates in young children hospitalized for severe RSV LRTI, according to the presence of underlying RSV risk factors, was conducted. The weighted mean case fatality rate was 1.2% (range, 0-8.3%; median, 0%; n = 10) among preterm infants; 5.2% (range, 2.0-37.0%; median, 5.9%; n = 7) among children with CHD; and 4.1% (range, 0-10.5%; median, 7.0%; n = 6) among children with BPD. Case fatality estimates among children not at high risk (n = 6) ranged from 0% to 1.5% (weighted mean, 0.2%; median, 0.0%). Fatality during hospitalization for severe RSV LRTI is rare among children not at high risk, but occurs more commonly among children at higher risk of RSV LRTI. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：S1 / S8

页数：8

共 49 条

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