Indole-beta-nucleophilic substitution .9. Nitrogen nucleophiles. Syntheses of hydroxycryptolepine, cryptolepine, and quindoline

被引：53

作者：

Cooper, MM ^{[1
]}

Lovell, JM ^{[1
]}

Joule, JA ^{[1
]}

机构：

[1] UNIV MANCHESTER,DEPT CHEM,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 24期

关键词：

D O I：

10.1016/0040-4039(96)00818-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The alkaloids hydroxycryptolepine, cryptolepine and quindoline have been synthesised utilising the intramolecular beta-nucleophilic substitution of a 1-phenylsulfonyl-2-acylindole. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：4283 / 4286

页数：4

共 15 条

[1] New alkaloids from Cryptolepis sanguinolenta [J].

Cimanga, K ;

DeBruyne, T ;

Pieters, L ;

Claeys, M ;

Vlietinck, A .

TETRAHEDRON LETTERS, 1996, 37 (10) :1703-1706

[2]

CIMANGA K, 1995, IN PRESS PLANTA MED

[3] INDOLE BETA-NUCLEOPHILIC SUBSTITUTION .2. FORMATION OF A [2]BENZOXEPINO[4,3-B]INDOLE AND A PYRIDO[4',3'-5,6]OXEPINO[3,2-B]INDOLE [J].

COOPER, MM ;

HIGNETT, GJ ;

JOULE, JA .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (12) :3008-3011

[4] NUCLEOPHILIC SUBSTITUTIONS AT AN INDOLE BETA-POSITION [J].

COOPER, MM ;

HIGNETT, GJ ;

NEWTON, RF ;

JOULE, JA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1977, (13) :432-434

[5]

DALTON L, 1983, J CHEM SOC PERK T 1, P2417, DOI 10.1039/p19830002417

[6] CONSTITUENTS OF WEST-AFRICAN MEDICINAL-PLANTS .20. QUINDOLINE FROM CRYPTOLEPIS-SANGUINOLENTA [J].

DWUMABADU, D ;

AYIM, JSK ;

FIAGBE, NIY ;

KNAPP, JE ;

SCHIFF, PL ;

SLATKIN, DJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (03) :433-434

[7] DIE KONSTITUTION DES ALKALOIDS CRYPTOLEPIN [J].

GELLERT, E ;

RAYMONDHAMET ;

SCHLITTLER, E .

HELVETICA CHIMICA ACTA, 1951, 34 (02) :642-651

[8] STRUCTURE OF [2]BENZOXEPINO[4,3-B]INDOLE [J].

GLENDINNING, A ;

HUNTER, WN ;

JOULE, JA ;

LEONARD, GA .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1993, 49 :2126-2128

[9]

GRAEBE C, 1888, LIEBIGS ANN CHEM, V247, P288

[10] CARBAZOLES, CARBOLINES, AND RELATED COMPOUNDS .1. QUINDOLINE DERIVATIVES [J].

HOLT, SJ ;

PETROW, V .

JOURNAL OF THE CHEMICAL SOCIETY, 1947, (MAY) :607-611

← 1 2 →