Completed sequence of aflatoxin pathway gene cluster in Aspergillus parasiticus

被引：128
作者：
Yu, JJ [1 ]
Bhatnagar, D [1 ]
Cleveland, TE [1 ]
机构：
[1] USDA ARS, So Reg Res Ctr, New Orleans, LA 70124 USA
来源：
FEBS LETTERS | 2004年 / 564卷 / 1-2期
关键词：
gene cluster; pathway evolution; aflatoxin; mycotoxin; secondary metabolite; Aspergillus flavus;
D O I：
10.1016/S0014-5793(04)00327-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An 82-kb Aspergillus parasiticus genomic DNA region representing the completed sequence of the well-organized aflatoxin pathway gene cluster has been sequenced and annotated. In addition to the 19 reported and characterized aflatoxin pathway genes and the four sugar utilization genes in this cluster, we report here the identification of six newly identified genes which are putatively involved in aflatoxin formation. The function of these genes, the cluster organization and its significance in gene expression are discussed. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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收藏
页码：126 / 130
页数：5
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