Role of platelet biomarkers in inflammatory response

被引：108

作者：

Chen, Yufei ^{[1
]}

Zhong, Haoxuan ^{[1
]}

Zhao, Yikai ^{[1
]}

Luo, Xinping ^{[1
]}

Gao, Wen ^{[1
]}

机构：

[1] Fudan Univ, Dept Cardiol, Huashan Hosp, 12 Middle Wulumuqi Rd, Shanghai 200040, Peoples R China

来源：

BIOMARKER RESEARCH | 2020年 / 8卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Platelet; Inflammatory response; Immune regulation; Activation-related biomarkers; CLASS-I MOLECULES; ACTIVATED PLATELETS; MEGAKARYOCYTE DEVELOPMENT; PRESENT ANTIGEN; CC-CHEMOKINE; CELLS; IMMUNE; DENGUE; MICROPARTICLES; SURVIVAL;

D O I：

10.1186/s40364-020-00207-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Beyond hemostasis, thrombosis and wound healing, it is becoming increasingly clear that platelets play an integral role in inflammatory response and immune regulation. Platelets recognize pathogenic microorganisms and secrete various immunoregulatory cytokines and chemokines, thus facilitating a variety of immune effects and regulatory functions. In this review, we discuss recent advances in signaling of platelet activation-related biomarkers in inflammatory settings and application prospects to apply for disease diagnosis and treatment.

引用

页数：7

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