One-pot preparation of 7-hydroxyquinoline

被引：18

作者：

Cameron, M

Hoerrner, RS

McNamara, JM

Figus, M

Thomas, S

机构：

[1] Merck & Co Inc, Merck Res Labs, Dept Proc Res, Rahway, NJ 07065 USA

[2] Merck & Co Inc, Merck Res Labs, Dept Analyt Res, Rahway, NJ 07065 USA

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2006年 / 10卷 / 01期

关键词：

D O I：

10.1021/op0501545

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An efficient one-pot procedure for the four-step preparation of 7-hydroxyquinoline (1) from 3-N-tosylaminophenol (4) in 60% isolated yield, that reduces the risk of exposure to acrolein (2), is described.

引用

页码：149 / 152

页数：4

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