Asthma control: how it can be best assessed?

被引：7
作者：
Fu, Juan-juan [1 ,2 ]
McDonald, Vanessa M. [2 ,3 ]
Wang, Gang [1 ]
Gibson, Peter G. [2 ,4 ]
机构：
[1] Sichuan Univ, West China Hosp, Dept Integrated Tradit Chinese & Western Med, Resp Grp, Chengdu 610064, Peoples R China
[2] Univ Newcastle, Sch Hlth & Med, Prior Res Ctr Asthma & Resp Dis, New Lambton Hts, NSW, Australia
[3] Univ Newcastle, Sch Nursing & Midwifery, New Lambton Hts, NSW, Australia
[4] John Hunter Hosp, Dept Resp & Sleep Med, New Lambton Hts, NSW, Australia
来源：
CURRENT OPINION IN PULMONARY MEDICINE | 2014年 / 20卷 / 01期
基金：
澳大利亚国家健康与医学研究理事会;
关键词：
asthma control; biomarker; comorbidity; exacerbation; inflammation; EXHALED NITRIC-OXIDE; RANDOMIZED CONTROLLED-TRIAL; WELL-CONTROLLED ASTHMA; CONTROL QUESTIONNAIRE; AIRWAY INFLAMMATION; CLINICAL-PRACTICE; GINA CRITERIA; LUNG-FUNCTION; TEST ACT; EXACERBATIONS;
D O I：
10.1097/MCP.0000000000000003
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Purpose of reviewA control-based asthma assessment is recommended by guidelines, but questions remain about how to assess the level of asthma control, and how current control status relates to future risks and biomarkers of disease pathogenesis. This review summarizes recent published data relating to asthma control and describes the challenges created by currently available instruments.Recent findingsThe current literature continues to show the widespread use of various assessment instruments for asthma control, in particular those with composite scores. However, poor correlations exist between the different assessment tools, and these instruments lack diagnostic accuracy to differentiate uncontrolled asthma. Whereas the concept of asthma control has been extended to add an assessment of future risks to the clinical control, clinical asthma control as measured by current available assessment tools does not necessary relate to the intrinsic disease activity which is typically characterized by inflammation in asthma.SummaryThe application of asthma control assessment represents an improvement in asthma management. The measurement of underlying disease activity potentially by biomarkers to assess disease control will lead to an improved assessment of the overall control of asthma, and further studies addressing this are needed.
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页码：1 / 7
页数：7
相关论文
共 48 条
[1]   Intranasal steroids and the risk of emergency department visits for asthma [J].
Adams, RJ ;
Fuhlbrigge, AL ;
Finkelstein, JA ;
Weiss, ST .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 109 (04) :636-642
[2]   Comparison between two methods of asthma control evaluation based on individual perception [J].
Andrade Almeida, Paula Cristina ;
Souza-Machado, Adelmir ;
Leite, Mylene dos Santos ;
Mendes de Castro, Lourdes Alzimar ;
Carvalho Coelho, Ana Carla ;
Cruz, Constanca Sampaio ;
Cruz, Alvaro Augusto .
JORNAL BRASILEIRO DE PNEUMOLOGIA, 2012, 38 (03) :299-307
[3]  
[Anonymous], 1995, Global Strategy for Asthma Management and Prevention
[4]   Mild exacerbations and eosinophilic inflammation in patients with stable, well-controlled asthma after 1 year of follow-up [J].
Belda, J ;
Giner, JD ;
Casan, P ;
Sanchis, J .
CHEST, 2001, 119 (04) :1011-1017
[5]   Influence of comorbid conditions on asthma [J].
Boulet, L-P. .
EUROPEAN RESPIRATORY JOURNAL, 2009, 33 (04) :897-906
[6]   Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma The BASALT Randomized Controlled Trial [J].
Calhoun, William J. ;
Ameredes, Bill T. ;
King, Tonya S. ;
Icitovic, Nikolina ;
Bleecker, Eugene R. ;
Castro, Mario ;
Cherniack, Reuben M. ;
Chinchilli, Vernon M. ;
Craig, Timothy ;
Denlinger, Loren ;
DiMango, Emily A. ;
Engle, Linda L. ;
Fahy, John V. ;
Grant, J. Andrew ;
Israel, Elliot ;
Jarjour, Nizar ;
Kazani, Shamsah D. ;
Kraft, Monica ;
Kunselman, Susan J. ;
Lazarus, Stephen C. ;
Lemanske, Robert F., Jr. ;
Lugogo, Njira ;
Martin, Richard J. ;
Meyers, Deborah A. ;
Moore, Wendy C. ;
Pascual, Rodolfo ;
Peters, Stephen P. ;
Ramsdell, Joe ;
Sorkness, Christine A. ;
Sutherland, E. Rand ;
Szefler, Stanley J. ;
Wasserman, Stephen I. ;
Walter, Michael J. ;
Wechsler, Michael E. ;
Boushey, Homer A. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 308 (10) :987-997
[7]   Consistency of GINA criteria and childhood asthma control test on the determination of asthma control [J].
Erkocoglu, Mustafa ;
Akan, Aysegul ;
Civelek, Ersoy ;
Kan, Rojdan ;
Azkur, Dilek ;
Kocabas, Can N. .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2012, 23 (01) :34-39
[8]   Obesity Is a Determinant of Asthma Control Independent of Inflammation and Lung Mechanics [J].
Farah, Claude S. ;
Kermode, Jessica A. ;
Downie, Sue R. ;
Brown, Nathan J. ;
Hardaker, Kate M. ;
Berend, Norbert ;
King, Gregory G. ;
Salome, Cheryl M. .
CHEST, 2011, 140 (03) :659-666
[9]  
FitzGerald J Mark, 2006, Can Respir J, V13, P253
[10]   Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma [J].
Fu, Juan-juan ;
Baines, Katherine J. ;
Wood, Lisa G. ;
Gibson, Peter G. .
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 2013, 17 (04) :187-199
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