Lung Cancer Epidemiology, Risk Factors, and Prevention

被引:256
作者
de Groot, Patricia [1 ]
Munden, Reginald F. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Div Diagnost Imaging, Dept Diagnost Radiol, Houston, TX 77030 USA
关键词
Lung cancer; Epidemiology; Risk factors; Prevention; HUMAN PAPILLOMA-VIRUS; 2ND-HAND SMOKE; BETA-CAROTENE; EXPOSURE; MORTALITY; SUSCEPTIBILITY; CANNABIS; RADON; PREVALENCE; CARCINOMA;
D O I
10.1016/j.rcl.2012.06.006
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The greatest risk by far for developing lung cancer is cigarette smoking, but age, radon exposure, environmental pollution, occupational exposures, gender, race, and pre-existing lung disease also are important contributors. However, not all people with these risk factors develop lung cancer, and some without any known risk factor do, indicating the importance of genetic influences. Future advances in understanding and treating lung cancer will be based on genetic analysis. The most effective preventive measure is to never start or to stop cigarette smoking.
引用
收藏
页码:863 / +
页数:15
相关论文
共 84 条
[1]   Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening [J].
Aberle, Denise R. ;
Adams, Amanda M. ;
Berg, Christine D. ;
Black, William C. ;
Clapp, Jonathan D. ;
Fagerstrom, Richard M. ;
Gareen, Ilana F. ;
Gatsonis, Constantine ;
Marcus, Pamela M. ;
Sicks, JoRean D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) :395-409
[2]   Biologic damage resulting from exposure to tobacco smoke and from radon: implication for preventive interventions [J].
Alavanja, MCR .
ONCOGENE, 2002, 21 (48) :7365-7375
[3]   Cannabis use and risk of lung cancer: a case-control study [J].
Aldington, S. ;
Harwood, M. ;
Cox, B. ;
Weatherall, M. ;
Beckert, L. ;
Hansell, A. ;
Pritchard, A. ;
Robinson, G. ;
Beasley, R. .
EUROPEAN RESPIRATORY JOURNAL, 2008, 31 (02) :280-286
[4]  
Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group, 1994, N Engl J Med, V330, P1029, DOI 10.1056/NEJM199404143301501
[5]  
American Cancer Society, 2011, CANC PREV EARL DET F
[6]   DIETARY CARCINOGENS AND ANTICARCINOGENS - OXYGEN RADICALS AND DEGENERATIVE DISEASES [J].
AMES, BN .
SCIENCE, 1983, 221 (4617) :1256-1264
[7]  
[Anonymous], 1988, IARC Monogr Eval Carcinog Risks Hum, V43, P173
[8]  
[Anonymous], CIT GUID RAD
[9]  
[Anonymous], TOBACCO SCI POLICY P
[10]  
[Anonymous], 2006, The health consequences of involuntary exposure to tobacco smoke a report of the Surgeon General