The predictive value of neutrophil-to-lymphocyte ratio for chronic obstructive pulmonary disease: a systematic review and meta-analysis

被引：14

作者：

Guo, Rui ^{[1
]}

Li, Jia ^{[1
]}

Ma, Xiaorong ^{[1
]}

Pan, Lei ^{[1
]}

机构：

[1] Capital Med Univ, Beijing Shijitan Hosp, Dept Resp & Crit Care Med, Beijing 100038, Peoples R China

来源：

EXPERT REVIEW OF RESPIRATORY MEDICINE | 2020年 / 14卷 / 09期

关键词：

Predictive value; neutrophil-to-lymphocyte ratio; chronic obstructive pulmonary disease; meta-analysis; acute exacerbation COPD; INFLAMMATION; EXACERBATION;

D O I：

10.1080/17476348.2020.1776613

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Introduction There was inconsistent results regarding the associations of neutrophil to lymphocyte ratio (NLR) with the progression and prognosis of chronic obstructive pulmonary disease (COPD). Areas Covered This paper assess the role of NLR on the progression and prognosis of COPD using a meta-analytic approach. PubMed, EmBase, and the Cochrane library were systematically searched. The pooled weighted mean differences and odds ratios with 95% confidence intervals were applied for continuous and categorical variables using the random-effects model. Expect Commenatry NLR was significantly high when comparing COPD patients to healthy individuals, and acute exacerbation COPD to stable COPD. Moreover, elevated NLR were significantly associated with higher risk of mortality and exacerbation.

引用

页码：929 / 936

页数：8

共 46 条

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