Synthesis of ciprofloxacin-based compounds: A review

被引：37
作者：
Akhtar, Rabia [1 ]
Yousaf, Muhammad [1 ]
Naqvi, Syed Ali Raza [1 ]
Irfan, Muhammad [2 ]
Zahoor, Ameer Fawad [1 ]
Hussain, Abdullah Ijaz [1 ]
Chatha, Shahzad Ali Shahid [1 ]
机构：
[1] Govt Coll Univ, Inst Chem, Faisalabad 38000, Pakistan
[2] Govt Coll Univ, Fac Pharmaceut Sci, Dept Pharmaceut, Faisalabad, Pakistan
来源：
SYNTHETIC COMMUNICATIONS | 2016年 / 46卷 / 23期
关键词：
Antibacterial; antibiotic; ciprofloxacin; fluoroquinolones; tuberculosis; VITRO ANTIBACTERIAL ACTIVITY; PIPERAZINYL QUINOLONE DERIVATIVES; FLUOROQUINOLONE DERIVATIVES; ANTIMYCOBACTERIAL EVALUATION; 1,2,4-TRIAZOLE-CIPROFLOXACIN HYBRIDS; BIOLOGICAL EVALUATION; POTENTIAL ANTITUMOR; ACID-DERIVATIVES; COUMARIN MOIETY; ANTI-HIV;
D O I：
10.1080/00397911.2016.1234622
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ciprofloxacin is a broad-spectrum antibiotic that plays an important role in inhibiting the growth of both Gram-positive and Gram-negative bacteria. Medicinal chemists are extensively involved in the synthesis of novel ciprofloxacin derivatives, in search of new ciprofloxacin-based drugs with enhanced activity. This review article summarizes the major synthetic approaches involved in the synthesis of ciprofloxacin-based molecules.
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收藏
页码：1849 / 1879
页数：31
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