A two-channel responsive fluorescent probe with AIE characteristics and its application for selective imaging of superoxide anions in living cells

被引：112

作者：

Gao, Xiaoying ^{[1
,2
]}

Feng, Guangxue ^{[2
]}

Manghnani, Purnima Naresh ^{[2
]}

Hu, Fang ^{[2
]}

Jiang, Nan ^{[1
]}

Liu, Jianzhao ^{[1
]}

Liu, Bin ^{[2
]}

Sun, Jing Zhi ^{[1
]}

Tang, Ben Zhong ^{[1
,3
,4
]}

机构：

[1] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Hangzhou 310027, Zhejiang, Peoples R China

[2] Natl Univ Singapore, Dept Chem & Biomol Engn, 4 Engn Dr 4, Singapore 117585, Singapore

[3] Hong Kong Univ Sci & Technol, Dept Chem, Div Biomed Engn, Kowloon, Hong Kong, Peoples R China

[4] South China Univ Technol, State Key Lab Luminescent Mat & Devices, Guangdong Innovat Res Team, SCUT HKUST Joint Res Lab, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 10期

基金：

中国国家自然科学基金; 新加坡国家研究基金会;

关键词：

AGGREGATION-INDUCED EMISSION; IN-VIVO; LIVE CELLS; INFLAMMATION; GENERATION; RADICALS; BIOLOGY; STRESS; CANCER; INJURY;

D O I：

10.1039/c6cc09307h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A two-channel responsive and AIE-active fluorescent probe was developed to selectively detect superoxide anions in living cells, which can be used to track the endogenous superoxide anion level when cells undergo apoptosis and inflammation.

引用

页码：1653 / 1656

页数：4

共 35 条

[1] Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K+ channel function impairment after brain injury [J].