Effects of High and Low Fat Dairy Food on Cardio-Metabolic Risk Factors: A Meta-Analysis of Randomized Studies

被引:133
作者
Benatar, Jocelyne R. [1 ]
Sidhu, Karishma [1 ]
Stewart, Ralph A. H. [1 ]
机构
[1] Auckland City Hosp, Green Lane Cardiovasc Serv, Auckland, New Zealand
关键词
POSTMENOPAUSAL CHINESE WOMEN; BODY-WEIGHT; BLOOD-PRESSURE; CARDIOVASCULAR-DISEASE; MILK SUPPLEMENTATION; INFLAMMATORY MARKERS; SERUM-LIPIDS; YOUNG-WOMEN; CONSUMPTION; DIETARY;
D O I
10.1371/journal.pone.0076480
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Importance: Clear guidelines on the health effects of dairy food are important given the high prevalence of obesity, cardiovascular disease and diabetes, and increasing global consumption of dairy food. Objective: To evaluate the effects of increased dairy food on cardio metabolic risk factors. Data Sources: Searches were performed until April 2013 using MEDLINE, Science Direct, Google,Embase, the Cochrane Central Register of Controlled Trials, reference lists of articles, and proceedings of major meetings. Study Selection: Randomized controlled studies with healthy adults randomized to increased dairy food for more than one month without additional interventions. Data Extraction and Synthesis: A standard list was used to extract descriptive, methodological and key variables from all eligible studies. If data was not included in the published report corresponding authors were contacted. Results: 20 studies with 1677 participants with a median duration of dietary change of 26 (IQR 10-39) weeks and mean increase in dairy food intake of 3.6 (SD 0.92) serves/day were included. There was an increase in weight with low (+0.82, 0.35 to 1.28 kg, p<0.001) and whole fat dairy food (+0.41, 0.04 to 0.79kg, p=0.03), but no significant change in waist circumference (-0.07, -1.24 to 1.10 cm); HOMA -IR (-0.94, -1.93 to 0.04 units); fasting glucose (+1.32, 0.19 to 2.45 mg/dl); LDL-c (1.85,-2.89 to 6.60 mg/dl); HDL-c (-0.19, -2.10 to 1.71 mg/dl); systolic BP (-0.4, -1.6 to 0.8 mmHg); diastolic BP (-0.4, -1.7 to 0.8 mmHg) or CRP (-1.07, -2.54 to 0.39 mg/L). Changes in other cardio-metabolic risk factors were similar for low and whole fat dairy interventions. Limitations: Most clinical trials were small and of modest quality.. Conclusion: Increasing whole fat and low fat dairy food consumption increases weight but has minor effects on other cardio-metabolic risk factors.
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页数:12
相关论文
共 67 条
[1]   Effect of dairy consumption on weight and body composition in adults: a systematic review and meta-analysis of randomized controlled clinical trials [J].
Abargouei, A. S. ;
Janghorbani, M. ;
Salehi-Marzijarani, M. ;
Esmaillzadeh, A. .
INTERNATIONAL JOURNAL OF OBESITY, 2012, 36 (12) :1485-1493
[2]  
Agriculture UDo, 2012, US CHOOSEMYPLATE
[3]   The effect of low-fat versus whole-fat dairy product intake on blood pressure and weight in young normotensive adults [J].
Alonso, A. ;
Zozaya, C. ;
Vazquez, Z. ;
Alfredo Martinez, J. ;
Martinez-Gonzalez, M. A. .
JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2009, 22 (04) :336-342
[5]  
[Anonymous], N ENGL J MED
[6]   A clinical trial of the effects of dietary patterns on blood pressure [J].
Appel, LJ ;
Moore, TJ ;
Obarzanek, E ;
Vollmer, WM ;
Svetkey, LP ;
Sacks, FM ;
Bray, GA ;
Vogt, TM ;
Cutler, JA ;
Windhauser, MM ;
Lin, PH ;
Karanja, N .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (16) :1117-1124
[7]  
Association AD, 2013, DAIR WHAT CAN I EAT
[8]   International Tables of Glycemic Index and Glycemic Load Values: 2008 [J].
Atkinson, Fiona S. ;
Foster-Powell, Kaye ;
Brand-Miller, Jennie C. .
DIABETES CARE, 2008, 31 (12) :2281-2283
[9]   DIETARY MODIFICATION WITH DAIRY-PRODUCTS FOR PREVENTING VERTEBRAL BONE LOSS IN PREMENOPAUSAL WOMEN - A 3-YEAR PROSPECTIVE-STUDY [J].
BARAN, D ;
SORENSEN, A ;
GRIMES, J ;
LEW, R ;
KARELLAS, A ;
JOHNSON, B ;
ROCHE, J .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (01) :264-270
[10]   Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults [J].
Barr, SI ;
McCarron, DA ;
Heaney, RP ;
Dawson-Hughes, B ;
Berga, SL ;
Stern, JS ;
Oparil, S .
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 2000, 100 (07) :810-817