Epidemiological investigation and glycotyping of clinical Pseudomonas aeruginosa isolates from patients with cystic fibrosis by mass spectrometry: Association with multiple drug resistance

被引：4

作者：

Altman, Eleonora ^{[1
]}

Wang, Zhan ^{[1
]}

Aaron, Shawn D. ^{[2
,3
]}

Liu, Xin ^{[1
]}

Vandemheen, Katherine L. ^{[2
]}

Ferris, Wendy ^{[2
]}

Giesbrecht, Tracy ^{[2
]}

Li, Jianjun ^{[1
]}

机构：

[1] Natl Res Council Canada, Inst Biol Sci, Ottawa, ON K1A 0R6, Canada

[2] Ottawa Hlth Res Inst, Ottawa, ON K1H 8L6, Canada

[3] Univ Ottawa, Fac Med, Ottawa, ON K1H 8M5, Canada

来源：

JOURNAL OF MICROBIOLOGICAL METHODS | 2009年 / 76卷 / 02期

关键词：

Mass spectrometry; Lipopolysaccharide; Pseudomonas aeruginosa; Drug resistance; Cystic fibrosis; LIPOPOLYSACCHARIDE CORE; STRUCTURAL ELUCIDATION; POLYSACCHARIDE; STRAINS; MORTALITY; CEPACIA; CANADA; REGION; ROUGH;

D O I：

10.1016/j.mimet.2008.10.008

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The aim of the present investigation was to develop a novel approach for rapid identification and differentiation of Pseudomonas aeruginosa clones from Canadian cystic fibrosis patients by capillary electrophoresis-mass spectrometry. We screened R aeruginosa isolates for lipopolysaccharide structure and presence/absence of alginate and correlated these findings with antibiotic resistance patterns. Crown Copyright (c) 2008 Published by Elsevier B.V. All rights reserved.

引用

页码：204 / 208

页数：5

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