Epidemiological association between fasting plasma glucose and shortened APTT

被引：30

作者：

Lippi, Giuseppe ^{[1
]}

Franchini, Massimo ^{[2
]}

Targher, Giovanni ^{[3
]}

Montagnana, Martina ^{[1
]}

Salvagno, Gian Luca ^{[1
]}

Guidi, Gian Cesare ^{[1
]}

Favaloro, Emmanuel J. ^{[4
]}

机构：

[1] Univ Verona, Osped Policlin GB Rossi, Dipartimento Sci Morfol Biomed, Sez Chim Clin, I-37134 Verona, Italy

[2] Univ Parma, Azienda Osped, Serv Immunoematol & Trasfus, I-43100 Parma, Italy

[3] Univ Verona, Dipartimento Sci Biomed & Chirurg, Sez Endocrinol & Malattie Metab, I-37134 Verona, Italy

[4] Westmead Hosp, Dept Haematol, Inst Clin Pathol & Med Res, Westmead, NSW 2145, Australia

来源：

CLINICAL BIOCHEMISTRY | 2009年 / 42卷 / 1-2期

关键词：

Activated partial thromboplastin time; Fibrinogen; Thrombosis; Diabetes; Hyperglycemia; PARTIAL THROMBOPLASTIN TIME; DIABETES-MELLITUS; HYPERGLYCEMIA; COAGULATION; RISK;

D O I：

10.1016/j.clinbiochem.2008.10.012

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objectives: To investigate the relationship between fasting plasma glucose (FPG) and shortened activated partial thromboplastin time (APTT), an independent risk factor for thrombosis. Design and methods: We analyzed outpatients' results of coagulation tests and FPG. Results: When compared with euglycemic subjects, those with impaired fasting glucose and diabetes displayed significantly shortened APTTs. Conclusions: This previously unreported association deserves scrutiny, because APTT is relatively inexpensive and it might identify diabetic patients at major risk of thrombosis. (C) 2008 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

引用

页码：118 / 120

页数：3

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