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Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Natl Clin Res Ctr Blood Dis, Hematopoiet Stem Cell Transplantat Ctr,State Key, 288 Nanjing Rd, Tianjin 300020, Peoples R China Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Natl Clin Res Ctr Blood Dis, Hematopoiet Stem Cell Transplantat Ctr,State Key, 288 Nanjing Rd, Tianjin 300020, Peoples R China