Risk factors for imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units in south China

被引:12
作者
Rao, Y. B. [1 ,2 ]
Ren, Z. X. [1 ,2 ]
Zhong, J. J. [1 ]
Zhong, X. M. [1 ,2 ]
Cao, B. [3 ]
Chen, D. M. [4 ]
Pan, X. N. [5 ]
Jia, Y. P. [6 ]
Gao, P. M. [7 ]
Yang, B. Y. [8 ]
Zhong, Q. [9 ]
Yang, J. [1 ]
机构
[1] Guangdong Women & Children Hosp, Dept Neonatol, Guangzhou, Guangdong, Peoples R China
[2] Guang Zhou Med Univ, Guangzhou, Guangdong, Peoples R China
[3] Women & Childrens Hosp Hunan Prov, Dept Neonatol, Changsha, Hunan, Peoples R China
[4] Women & Childrens Hosp Quanzhou, Dept Neonatol, Quanzhou, Fujian, Peoples R China
[5] Women & Childrens Hosp Guangxi Zhuang Autonomous, Dept Neonatol, Nanning, Guangxi, Peoples R China
[6] Womens & Childrens Hosp, Dept Neonatol, Haikou, Hainan, Peoples R China
[7] Women & Childrens Hosp Foshan, Dept Neonatol, Foshan, Guangdong, Peoples R China
[8] Women & Childrens Hosp Zhongshan, Dept Neonatol, Zhongshan, Guangdong, Peoples R China
[9] Women & Childrens Hosp Shenzhen, Dept Neonatol, Shenzhen, Guangdong, Peoples R China
关键词
Neonate; Pseudomonas aeruginosa; Imipenem; Hospital-acquired infection; NOSOCOMIAL INFECTION;
D O I
10.1016/j.jhin.2017.12.016
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This multi-centre retrospective study was designed to investigate the risk factors for infection with imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units (NICUs) in south China. All patients with confirmed P. aeruginosa infection from eight NICUs in south China were divided into two groups: imipenem-susceptible P. aeruginosa and imipenem-resistant P. aeruginosa. Data were analysed using Chi-squared test and logistic regression. In total, 188 medical records were reviewed. On multi-variate logistic analysis, the only independent risk factor was imipenem treatment within two weeks of isolation of P. aeruginosa (odds ratio 6.409, 95% confidence interval 1.926-21.333). (C) 2017 The Authors. Published by Elsevier Ltd on behalf of The Healthcare Infection Society.
引用
收藏
页码:305 / 308
页数:4
相关论文
共 50 条
[31]   Investigation and Control of an Outbreak of Imipenem-resistant Acinetobacter baumannii Infection in a Pediatric Intensive Care Unit [J].
Hong, Ki Bae ;
Oh, Hyang Soon ;
Song, Jeong Suk ;
Lim, Ji-hee ;
Kang, Dong Ki ;
Son, Ihn Suk ;
Park, June Dong ;
Kim, Eui Chong ;
Lee, Hoan Jong ;
Choi, Eun Hwa .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2012, 31 (07) :685-690
[32]   Re-sensitization of imipenem-resistant Pseudomonas aeruginosa and restoration of cephalosporins susceptibility in Enterobacteriaceae by recombinant Esterase B [J].
Whangsuk, Wirongrong ;
Dulyayangkul, Punyawee ;
Loprasert, Suvit ;
Dubbs, James M. ;
Vattanaviboon, Paiboon ;
Mongkolsuk, Skorn .
LETTERS IN APPLIED MICROBIOLOGY, 2024, 77 (12)
[33]   Insertion sequence ISRP10 inactivation of the oprD gene in imipenem-resistant Pseudomonas aeruginosa clinical isolates [J].
Sun, Qinghui ;
Ba, Zhaofen ;
Wu, Guoying ;
Wang, Wei ;
Lin, Shuxiang ;
Yang, Hongjiang .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2016, 47 (05) :375-379
[34]   Antibiotic utilization and Pseudomonas aeruginosa resistance in intensive care units [J].
Vojtova, Vladimira ;
Kolar, Milan ;
Hricova, Kristyna ;
Uvizl, Radek ;
Neiser, Jan ;
Blahut, Ladislav ;
Urbanek, Karel .
NEW MICROBIOLOGICA, 2011, 34 (03) :291-298
[35]   Is surveillance of Pseudomonas aeruginosa carriage in intensive care units useful? [J].
Slekovec, C. ;
Navellou, J. -C. ;
Blasco, G. ;
Thouverez, M. ;
Bertrand, X. ;
Talon, D. .
ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION, 2010, 29 (04) :279-282
[36]   Pseudomonas aeruginosa clonal dissemination in Brazilian intensive care units [J].
Figueiredo-Mendes, CM ;
Sinto, S ;
Mello-Sampaio, JL ;
Cardoso-Leao, S ;
Oplustil, CP ;
Turner, P ;
Veiga-Kiffer, CR .
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, 2005, 23 (07) :402-405
[37]   Epidemiology of Pseudomonas aeruginosa and risk factors for carriage acquisition in an intensive care unit [J].
Thuong, M ;
Arvaniti, K ;
Ruimy, R ;
de la Salmonière, P ;
Scanvic-Hameg, A ;
Lucet, JC ;
Régnier, B .
JOURNAL OF HOSPITAL INFECTION, 2003, 53 (04) :274-282
[38]   Overproduction of active efflux pump and variations of OprD dominate in imipenem-resistant Pseudomonas aeruginosa isolated from patients with bloodstream infections in Taiwan [J].
Kao, Cheng-Yen ;
Chen, Shu-Sheng ;
Hung, Kuei-Hsiang ;
Wu, Hsiu-Mei ;
Hsueh, Po-Ren ;
Yan, Jing-Jou ;
Wu, Jiunn-Jong .
BMC MICROBIOLOGY, 2016, 16
[39]   Risk factors and molecular typing associated with colonization or infection by a multidrug-resistant (MDR) Pseudomonas aeruginosa in intensive care unit (ICU) patients [J].
S Milas ;
M Piagnerelli ;
M Vanhaeverbeek ;
E Carlier ;
A Deplano ;
D Govaerts .
Critical Care, 7 (Suppl 2)
[40]   Risk Factors and Outcomes of Patients with Pseudomonas aeruginosa Bloodstream Infection in the Intensive Care Unit [J].
Caydasi, Ozge ;
Arsian, Eytup ;
Cetin, Ayse Sababli ;
Karadag, Fatma Yilmaz ;
Dede, Asiye Tuncel ;
Adiyeke, Esra ;
Gundogus, Narin ;
Engin, Derya Ozturk .
JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2024, 17 (08)