Early Phase of the COVID-19 Outbreak in Hungary and Post-Lockdown Scenarios

被引:41
作者
Rost, Gergely [1 ]
Bartha, Ferenc A. [1 ]
Bogya, Norbert [1 ]
Boldog, Peter [1 ]
Denes, Attila [1 ]
Ferenci, Tamas [2 ]
Horvath, Krisztina J. [1 ]
Juhasz, Attila [1 ,3 ]
Nagy, Csilla [1 ,3 ]
Tekeli, Tamas [1 ]
Vizi, Zsolt [1 ]
Oroszi, Beatrix [1 ]
机构
[1] Univ Szeged, Bolyai Inst, H-6720 Szeged, Hungary
[2] Obuda Univ, Physiol Controls Res Ctr, H-1034 Budapest, Hungary
[3] Govt Off Capital City Budapest, Dept Publ Hlth, H-1034 Budapest, Hungary
来源
VIRUSES-BASEL | 2020年 / 12卷 / 07期
关键词
COVID-19; epidemic; Hungary; under-ascertainment; SARS-CoV-2; compartmental model; reproduction number; intervention; case fatality rate; TIME;
D O I
10.3390/v12070708
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
COVID-19 epidemic has been suppressed in Hungary due to timely non-pharmaceutical interventions, prompting a considerable reduction in the number of contacts and transmission of the virus. This strategy was effective in preventing epidemic growth and reducing the incidence of COVID-19 to low levels. In this report, we present the first epidemiological and statistical analysis of the early phase of the COVID-19 outbreak in Hungary. Then, we establish an age-structured compartmental model to explore alternative post-lockdown scenarios. We incorporate various factors, such as age-specific measures, seasonal effects, and spatial heterogeneity to project the possible peak size and disease burden of a COVID-19 epidemic wave after the current measures are relaxed.
引用
收藏
页数:30
相关论文
共 73 条
[1]  
Allieta M, 2020, COVID 19 OUTBREAK IT, DOI [10.1101/2020.05.12.20076794, DOI 10.1101/2020.05.12.20076794]
[2]  
[Anonymous], 2020, H UNCOVER RESZ 8276
[3]  
[Anonymous], 2020, TAJ OLD KOR
[4]   COVID-19 and the consequences of isolating the elderly [J].
Armitage, Richard ;
Nellums, Laura B. .
LANCET PUBLIC HEALTH, 2020, 5 (05) :E256-E256
[5]   Seasonal transmission potential and activity peaks of the new influenza A(H1N1): a Monte Carlo likelihood analysis based on human mobility [J].
Balcan, Duygu ;
Hu, Hao ;
Goncalves, Bruno ;
Bajardi, Paolo ;
Poletto, Chiara ;
Ramasco, Jose J. ;
Paolotti, Daniela ;
Perra, Nicola ;
Tizzoni, Michele ;
Van den Broeck, Wouter ;
Colizza, Vittoria ;
Vespignani, Alessandro .
BMC MEDICINE, 2009, 7 :45
[6]  
Barbarossa M.V., 2020, MEDRV, DOI [10.1101/2020.04.08.20056630, DOI 10.1101/2020.04.08.20056630]
[7]  
Blyuss K. B., 2020, EFFECTS LATENCY AGE
[8]   Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series [J].
Boehmer, Merle M. ;
Buchholz, Udo ;
Corman, Victor M. ;
Hoch, Martin ;
Katz, Katharina ;
Marosevic, Durdica, V ;
Boehm, Stefanie ;
Woudenberg, Tom ;
Ackermann, Nikolaus ;
Konrad, Regina ;
Eberle, Ute ;
Treis, Bianca ;
Dangel, Alexandra ;
Bengs, Katja ;
Fingerle, Volker ;
Berger, Anja ;
Hoermansdorfer, Stefan ;
Ippisch, Siegfried ;
Wicklein, Bernd ;
Grahl, Andreas ;
Poertner, Kirsten ;
Muller, Nadine ;
Zeitlmann, Nadine ;
Boender, T. Sonia ;
Cai, Wei ;
Reich, Andreas ;
an der Heiden, Maria ;
Rexroth, Ute ;
Hamouda, Osamah ;
Schneider, Julia ;
Veith, Talitha ;
Muehlemann, Barbara ;
Woelfel, Roman ;
Antwerpen, Markus ;
Walter, Mathias ;
Protzer, Ulrike ;
Liebl, Bernhard ;
Haas, Walter ;
Sing, Andreas ;
Drosten, Christian ;
Zapf, Andreas .
LANCET INFECTIOUS DISEASES, 2020, 20 (08) :920-928
[9]   Risk Assessment of Novel Coronavirus COVID-19 Outbreaks Outside China [J].
Boldog, Peter ;
Tekeli, Tamas ;
Vizi, Zsolt ;
Denes, Attila ;
Bartha, Ferenc A. ;
Rost, Gergely .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[10]  
Bolyai Institute University of Szeged, 2020, COD BAS COVID 19 MOD