Catalysts for enantioselective Biginelli reaction based on the composite silica-zirconia xerogels prepared using different zirconium sources

被引：14

作者：

Krivtsov, I. V. ^{[1
]}

Titova, Yu. A. ^{[2
]}

Ilkaeva, M. V. ^{[1
]}

Avdin, V. V. ^{[1
]}

Fedorova, O. V. ^{[2
]}

Khainakov, S. A. ^{[3
]}

Garcia, J. R. ^{[3
]}

Rusinov, G. L. ^{[2
]}

Charushin, V. N. ^{[2
]}

机构：

[1] South Ural State Univ, Chelyabinsk, Russia

[2] I Ya Postovsky Inst Organ Synth RAS, Urals Branch, Ekaterinburg, Russia

[3] Univ Oviedo, E-33006 Oviedo, Spain

来源：

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY | 2014年 / 69卷 / 02期

基金：

俄罗斯基础研究基金会;

关键词：

Silica-zirconia; Biginelli reaction; Enantioselective catalyst; Sol-gel method; ONE-POT SYNTHESIS; OXIDES; ACID;

D O I：

10.1007/s10971-013-3242-z

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The composite silica-zirconia xerogels have been prepared via sol-gel method using zirconium oxychloride, oxynitrate, acetate and sodium silicate as the precursors. The prepared materials have been characterized using FTIR, TG/DTA, EDX and surface area analyses. It has been established that surface area of silica-zirconia xerogels significantly depends on the zirconium source, but phase transitions and structural features of the xerogels seem to be unaffected by the choice of the zirconia precursor. Prepared xerogels increase the activity of chiral inductor in the asymmetric Biginelli reaction. The anion of the zirconium salt adsorbed on the surface of the synthesized material and the presence of Si-O-Zr heterolinkages determines the reaction yield. The highest chemo- and enantioselectivity towards formation of ee isomer have been provided by the catalyst prepared from zirconium oxychloride.

引用

页码：448 / 452

页数：5

共 17 条

[1] Thermal behavior of the composite xerogels of zirconium oxyhydroxide and silicic acid [J].