Antiplatelet therapies for secondary stroke prevention: an update on clinical and cost-effectiveness

被引:0
作者
Rothlisberger, Julia M. [1 ]
Ovbiagele, Bruce [1 ]
机构
[1] Med Univ S Carolina, Dept Neurol, Charleston, SC 29425 USA
关键词
antiplatelet; antithrombotics; cost; outcomes; prevention; stroke; TRANSIENT ISCHEMIC ATTACK; EXTENDED-RELEASE DIPYRIDAMOLE; ACUTE CORONARY SYNDROMES; DOUBLE-BLIND; CLOPIDOGREL; ASPIRIN; TRIAL; GUIDELINES; PRASUGREL; EFFICACY;
D O I
10.2217/CER.15.22
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Stroke exacts a huge toll physically, mentally and economically. Antiplatelet therapy is the cornerstone of secondary stroke prevention, and proven drugs available to successfully realize this therapeutic strategy for the long term include aspirin, dipyridamole plus aspirin and clopidogrel. However, government agencies, corporations, health plans and patients desire more information about the clinical- and cost-effectiveness of these established therapies in real-world settings. This paper provides an update on evidence-based secondary stroke prevention with antiplatelet medications, discusses cost-related issues and offers perspective about the future.
引用
收藏
页码:377 / 384
页数:8
相关论文
共 40 条
[1]   CLASSIFICATION OF SUBTYPE OF ACUTE ISCHEMIC STROKE - DEFINITIONS FOR USE IN A MULTICENTER CLINICAL-TRIAL [J].
ADAMS, HP ;
BENDIXEN, BH ;
KAPPELLE, LJ ;
BILLER, J ;
LOVE, BB ;
GORDON, DL ;
MARSH, EE ;
KASE, CS ;
WOLF, PA ;
BABIKIAN, VL ;
LICATAGEHR, EE ;
ALLEN, N ;
BRASS, LM ;
FAYAD, PB ;
PAVALKIS, FJ ;
WEINBERGER, JM ;
TUHRIM, S ;
RUDOLPH, SH ;
HOROWITZ, DR ;
BITTON, A ;
MOHR, JP ;
SACCO, RL ;
CLAVIJO, M ;
ROSENBAUM, DM ;
SPARR, SA ;
KATZ, P ;
KLONOWSKI, E ;
CULEBRAS, A ;
CAREY, G ;
MARTIR, NI ;
FICARRA, C ;
HOGAN, EL ;
CARTER, T ;
GURECKI, P ;
MUNTZ, BK ;
RAMIREZLASSEPAS, M ;
TULLOCH, JW ;
QUINONES, MR ;
MENDEZ, M ;
ZHANG, SM ;
ALA, T ;
JOHNSTON, KC ;
ANDERSON, DC ;
TARREL, RM ;
NANCE, MA ;
BUDLIE, SR ;
DIERICH, M ;
HELGASON, CM ;
HIER, DB ;
SHAPIRO, RA .
STROKE, 1993, 24 (01) :35-41
[2]  
[Anonymous], 2022, Lost in Transcription: Auto-Captions Often Fall Short on Zoom, Facebook, Google Meet, and YouTube
[3]  
[Anonymous], SOCRATES AC STROK TR
[4]  
Baigent C, 2002, BMJ-BRIT MED J, V324, P71, DOI 10.1136/bmj.324.7329.71
[5]   Statistical analysis plan for the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial [J].
Bath, Philip M. W. ;
Robson, Katie ;
Woodhouse, Lisa J. ;
Sprigg, Nikola ;
Dineen, Robert ;
Pocock, Stuart .
INTERNATIONAL JOURNAL OF STROKE, 2015, 10 (03) :449-451
[6]   Effects of Clopidogrel Added to Aspirin in Patients with Recent Lacunar Stroke [J].
Benavente, Oscar R. ;
Hart, Robert G. ;
McClure, Leslie A. ;
Szychowski, Jeffrey M. ;
Coffey, Christopher S. ;
Pearce, Lesly A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (09) :817-825
[7]   Cost-effectiveness analysis of antiplatelet therapy in the prevention of recurrent stroke in the UK - Aspirin, dipyridamole and aspirin-dipyridamole [J].
Chambers, M ;
Hutton, J ;
Gladman, J .
PHARMACOECONOMICS, 1999, 16 (05) :577-593
[8]   Anti-platelet therapy and managing ulcer risk [J].
Chan, Francis K. L. .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2012, 27 (02) :195-199
[9]   Full Coverage for Preventive Medications after Myocardial Infarction [J].
Choudhry, Niteesh K. ;
Avorn, Jerry ;
Glynn, Robert J. ;
Antman, Elliott M. ;
Schneeweiss, Sebastian ;
Toscano, Michele ;
Reisman, Lonny ;
Fernandes, Joaquim ;
Spettell, Claire ;
Lee, Joy L. ;
Levin, Raisa ;
Brennan, Troyen ;
Shrank, William H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (22) :2088-2097
[10]   Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation [J].
Connolly, S. J. ;
Yusuf, S. ;
Camm, J. ;
Chrolavicius, S. ;
Commerford, P. ;
Flather, M. ;
Hart, R. G. ;
Hohnloser, S. H. ;
Joyner, C. ;
Pfeffer, M. ;
Gaudin, C. ;
Blumenthal, M. ;
Marchese, C. ;
Pogue, J. ;
Hart, R. ;
Hohnloser, S. ;
Anand, I. ;
Arthur, H. ;
Avezum, A. ;
Budaj, A. ;
Ceremuzynski, L. ;
De Caterina, R. ;
Diaz, R. ;
Dorian, P. ;
Flaker, G. ;
Fox, K. A. A. ;
Franzosi, M. G. ;
Goldhaber, S. ;
Golitsyn, S. ;
Granger, C. ;
Halon, D. ;
Hermosillo, A. ;
Hunt, D. ;
Jansky, P. ;
Karatzas, N. ;
Keltai, M. ;
Kozan, O. ;
Lanas, F. ;
Lau, P. ;
Le Heuzey, J. Y. ;
Lewis, B. S. ;
Morais, J. ;
Morillo, C. ;
Paolasso, E. ;
Peters, R. J. ;
Pfisterer, M. ;
Piegas, L. ;
Pipilis, A. ;
Sitkei, E. ;
Swedberg, K. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (20) :2066-2078