Experimental characterization of monolithic-crystal small animal PET detectors read out by APD arrays

被引:63
作者
Maas, Marnix C. [1 ]
van der Laan, D. J.
Schaart, Dennis R.
Huizenga, Jan
Brouwer, J. C.
Bruyndonckx, Peter
Leonard, Sophie
Lemaitre, Cedric
van Eijk, Carel W. E.
机构
[1] Delft Univ Technol, NL-2629 JB Delft, Netherlands
[2] Vrije Univ Brussels, Inter Univ Inst High Energies, B-1050 Brussels, Belgium
关键词
angle of incidence; avalanche photodiode (APD); depth-of-interaction; monolithic scintillator crystals; nearest neighbor method; positron emission tomography (PET); spatial resolution;
D O I
10.1109/TNS.2006.873711
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Minimizing dead space is one way to increase the detection efficiency of small-animal PET scanners. By using monolithic scintillator crystals (e.g., 20 mm x 10 mm x 10 mm LSO), loss of efficiency due to inter-crystal reflective material is minimized. Readout of such crystals can be performed by means of one or more avalanche photo-diode (APD) arrays optically coupled to the crystal. The entry point of a gamma photon on the crystal surface can be estimated from the measured distribution of the scintillation light over the APD array(s). By estimating the entry point, correction for the depth-of-interaction (DOI) is automatically provided. We are studying the feasibility of such detector modules. To this end, a 64-channel test setup has been developed. Experiments to determine the effect on the spatial resolution of crystal surface finish and detector geometry have been carried out. The first results of these experiments are presented and compared to simulation results. The crystal surface finish has only a small influence on the spatial resolution. The spatial resolution of 20 mm x 10 nun x 10 mm detectors is significantly better when read out on the front side than when read out on the back side. With a 20 mm x 10 mm x 20 mm crystal coupled to two APD arrays, a very small resolution degradation of only similar to 0.2 min is observed for an incidence angle of 30 degrees compared to normal incidence.
引用
收藏
页码:1071 / 1077
页数:7
相关论文
共 15 条
[1]  
ADAM LE, 2000, P IEEE NSS, V3, P17
[2]   3D position readout from thick scintillators [J].
Antich, P ;
Malakhov, N ;
Parkey, R ;
Slavin, N ;
Tsyganov, E .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2002, 480 (2-3) :782-787
[3]   Neural network-based position estimators for PET detectors using monolithic LSO blocks [J].
Bruyndonckx, P ;
Léonard, S ;
Tavernier, S ;
Lemaître, C ;
Devroede, O ;
Wu, YB ;
Krieguer, M .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2004, 51 (05) :2520-2525
[4]   Study of spatial resolution and depth of interaction of APD-based PET detector modules using light sharing schemes [J].
Bruyndonckx, P ;
Léonard, S ;
Liu, JG ;
Tavernier, S ;
Szupryczynski, P ;
Fedorov, A .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2003, 50 (05) :1415-1419
[5]  
CLEMENT D, 1998, P IEEE NSS, V3, P1448
[6]   NEAREST NEIGHBOR PATTERN CLASSIFICATION [J].
COVER, TM ;
HART, PE .
IEEE TRANSACTIONS ON INFORMATION THEORY, 1967, 13 (01) :21-+
[7]   Use of a neural network to exploit light division in a triangular scintillating crystal [J].
Delorme, S ;
Frei, R ;
Joseph, C ;
Loude, JF ;
Morel, C .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1996, 373 (01) :111-118
[8]   Design optimization of the PMT-ClearPET prototypes based on simulation studies with GEANT3 [J].
Heinrichs, U ;
Pietrzyk, U ;
Ziemons, K .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2003, 50 (05) :1428-1432
[9]  
KHODAVERDI M, 2001, P IEEE NSS, V3, P1605
[10]   Design of a small animal MR compatible PET scanner [J].
Slates, R ;
Cherry, S ;
Boutefnouchet, A ;
Shao, YP ;
Dahlbom, M ;
Farahani, K .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1999, 46 (03) :565-570