Design of a "Turn-Off/Turn-On" Biosensor: Understanding Carbohydrate-Lectin Interactions for Use in Noncovalent Drug Delivery

被引：62

作者：

Gorityala, Bala Kishan ^{[1
]}

Lu, Zhiqiang ^{[1
]}

Leow, Min Li ^{[1
]}

Ma, Jimei ^{[1
]}

Liu, Xue-Wei ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 37期

关键词：

GOLD NANOPARTICLES; CONCANAVALIN-A; FLUORESCENCE; TRANSPORT; BINDING; PROBES; ACID;

D O I：

10.1021/ja306288p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A low-cost and highly sensitive biosensor system is designed to investigate carbohydrate-lectin interactions. This combination of glyco-gold nanoparticles and boronic acid biosensor system opens a way to study noncovalent drug delivery.

引用

页码：15229 / 15232

页数：4

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