New therapies for systemic lupus erythematosus: Cellular targets

被引：14
作者：
Looney, RJ [1 ]
Anolik, J [1 ]
Sanz, I [1 ]
机构：
[1] Univ Rochester, Sch Med & Dent, Dept Med, Brockport, NY 14420 USA
来源：
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2006年 / 32卷 / 01期
关键词：
D O I：
10.1016/j.rdc.2005.09.007
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antilymphocyte antibodies have been widely used in oncology and transplantation and are now being tested in autoimmune diseases. For systemic lupus erythematosus, anti-B-cell antibodies are furthest along in development. This article discusses the B-cell abnormalities found in systemic lupus erythematosus and the clinical and immunologic effects of anti-B-cell therapies.
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页码：201 / +
页数：16
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