Solid-state systems of biological recognition based on macroporous polymer monoliths

被引:3
作者
Vlakh, E. G. [1 ]
Korzhikov, V. A. [1 ]
Tennikova, T. B. [1 ]
机构
[1] Russian Acad Sci, Inst Macromol Cpds, St Petersburg 199004, Russia
基金
俄罗斯基础研究基金会;
关键词
flow biological recognition systems; affinity chromatography; heterogeneous biocatalysis; biological microchips; macroporous monolithic sorbents; synthesis; proteins; enzymes; DNA; oligonucleotides; viruses; modeling of interactions; PERFORMANCE MEMBRANE CHROMATOGRAPHY; IMMOBILIZED ENZYME REACTORS; PHASE PEPTIDE-SYNTHESIS; AFFINITY-CHROMATOGRAPHY; LIQUID-CHROMATOGRAPHY; PERFUSION CHROMATOGRAPHY; POLYCLONAL ANTIBODIES; POROUS STRUCTURE; HIGH-THROUGHPUT; PACKED-COLUMNS;
D O I
10.1007/s11172-012-0137-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The review summarizes the results of long-term studies having a general idea of the modeling of solid-state processes based on the principle of biological recognition. In all studies considered in this review, new-generation stationary phases, so-called macroporous monolithic sorbents, were used as supporting media. The developed biological recognition systems established the basis of the methods for the fine isolation and highly sensitive analysis of biological substances having different structures and functionality.
引用
收藏
页码:937 / 961
页数:25
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