Recovery of corneal sensitivity after laser-assisted subepithelial keratectomy

PURPOSE: To evaluate the recovery of corneal sensitivity after laser-assisted subepithelial keratectomy (LASEK) for myopia. SETTING: Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China. METHODS: In this prospective interventional case series, central corneal sensitivity (CCS) was measured using a Cochet-Bonnet esthesiometer (Luneau Ophthalmologie) in 85 eyes of 50 patients before and 2 weeks, 1 month, 3 months, and 6 months after LASEK for the treatment of myopia. For analysis, the eyes were divided into 2 groups-the low-moderate myopia group (spherical equivalent [SE] - 1.0 to -6.0 diopters [D]) and the high myopia group (SE -6.0 to - 16.0 D)-and the correlation between ablation depth and CCS was evaluated. RESULTS: In both groups, a significant decrease in CCS was present at 2 weeks and 1 month. In the low-moderate myopia group, the CCS recovered to preoperative values at 3 months. In the high myopia group, recovery of CCS was slower and preoperative values were reached only at the 6-month follow-up. Measured CCS was significantly correlated with the ablation depth used at the 3-month and 6-month examinations (r = -0.262 and r = -0.264, respectively; P<.05). CONCLUSION: Recovery of corneal sensitivity began 1 month after LASEK and was completed by 3 months in eyes treated for low-moderate myopia and at 6 months in eyes with high myopia. The depth of ablation during surgery affected the recovery of corneal sensitivity.