The Osteoarthritis Initiative (OAI) magnetic resonance imaging quality assurance update

被引:28
作者
Schneider, E. [1 ,2 ]
NessAiver, M. [3 ]
机构
[1] Cleveland Clin Fdn, Imaging Inst, Cleveland, OH 44116 USA
[2] SciTrials LLC, Rocky River, OH USA
[3] SimplyPhysics LLC, Baltimore, MD USA
关键词
Magnetic resonance; Quality assurance (QA); Clinical trial; Osteoarthritis Initiative; GEOMETRIC DISTORTION; ARTICULAR-CARTILAGE; TEST OBJECTS; MRI; PERFORMANCE; PHANTOM; REPRODUCIBILITY; PROTOCOLS; SYSTEMS; TRIAL;
D O I
10.1016/j.joca.2012.10.011
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Objective: Longitudinal quantitative evaluation of cartilage disease requires reproducible measurements over time. We report 8 years of quality assurance (QA) metrics for quantitative magnetic resonance (MR) knee analyses from the Osteoarthritis Initiative (OAI) and show the impact of MR system, phantom, and acquisition protocol changes. Method: Key 3 T MR QA metrics, including signal-to-noise, signal uniformity, T2 relaxation times, and geometric distortion, were quantified monthly on two different phantoms using an automated program. Results: Over 8 years, phantom measurements showed root-mean-square coefficient-of-variation reproducibility of <0.25% (190.0 mm diameter) and <0.20% (148.0 mm length), resulting in spherical volume reproducibility of <0.35%. T2 relaxation time reproducibility varied from 1.5% to 5.3%; seasonal fluctuations were observed at two sites. All other QA goals were met except: slice thicknesses were consistently larger than nominal on turbo spin echo images; knee coil signal uniformity and signal level varied significantly over time. Conclusions: The longitudinal variations for a spherical volume should have minimal impact on the accuracy and reproducibility of cartilage volume and thickness measurements as they are an order of magnitude smaller than reported for either unpaired or paired (repositioning and reanalysis) precision errors. This stability should enable direct comparison of baseline and follow-up images. Cross-comparison of the geometric results from all four OAI sites reveal that the MR systems do not statistically differ and enable results to be pooled. MR QA results identified similar technical issues as previously published. Geometric accuracy stability should have the greatest impact on quantitative analysis of longitudinal change in cartilage volume and thickness precision. (C) 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:110 / 116
页数:7
相关论文
共 23 条
[1]  
American College of Radiology (ACR), PHANT TEST GUID ACR
[2]  
American College of Radiology (ACR), MRI ACCR PROGR REQ
[3]   Standardization of performance evaluation in MRI: 13 years' experience of intersystem comparison [J].
De Wilde, J ;
Price, D ;
Curran, J ;
Williams, J ;
Kitney, R .
CONCEPTS IN MAGNETIC RESONANCE, 2002, 15 (01) :111-116
[4]   Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis Initiative [J].
Eckstein, F ;
Hudelmaier, M ;
Wirth, W ;
Kiefer, B ;
Jackson, R ;
Yu, J ;
Eaton, CB ;
Schneider, E .
ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 (04) :433-441
[5]   Measurement of MRI scanner performance with the ADNI phantom [J].
Gunter, Jeffrey L. ;
Bernstein, Matt A. ;
Borowski, Brett J. ;
Ward, Chadwick P. ;
Britson, Paula J. ;
Felmlee, Joel P. ;
Schuff, Norbert ;
Weiner, Michael ;
Jack, Clifford R. .
MEDICAL PHYSICS, 2009, 36 (06) :2193-2205
[6]   Change in cartilage morphometry: a sample of the progression cohort of the Osteoarthritis Initiative [J].
Hunter, D. J. ;
Niu, J. ;
Zhang, Y. ;
Totterman, S. ;
Tamez, J. ;
Dabrowski, C. ;
Davies, R. ;
Le Graverand, M-P Hellio ;
Luchi, M. ;
Tymofyeyev, Y. ;
Beals, C. R. .
ANNALS OF THE RHEUMATIC DISEASES, 2009, 68 (03) :349-356
[7]   MRI SCANNER VARIABILITY STUDIES USING A SEMIAUTOMATED ANALYSIS SYSTEM [J].
HYDE, RJ ;
ELLIS, JH ;
GARDNER, EA ;
ZHANG, YT ;
CARSON, PL .
MAGNETIC RESONANCE IMAGING, 1994, 12 (07) :1089-1097
[8]   QUALITY ASSESSMENT IN IN-VIVO NMR-SPECTROSCOPY .4. A MULTICENTER TRIAL OF TEST OBJECTS AND PROTOCOLS FOR PERFORMANCE ASSESSMENT IN CLINICAL NMR-SPECTROSCOPY [J].
KEEVIL, SF ;
BARBIROLI, B ;
COLLINS, DJ ;
DANIELSEN, ER ;
HENNIG, J ;
HENRIKSEN, O ;
LEACH, MO ;
LONGO, R ;
LOWRY, M ;
MOORE, C ;
MOSER, E ;
SEGEBARTH, C ;
BOVEE, WMMJ ;
PODO, F .
MAGNETIC RESONANCE IMAGING, 1995, 13 (01) :139-157
[9]   REPRODUCIBILITY OF T1 AND T2 RELAXATION-TIMES CALCULATED FROM ROUTINE MR IMAGING SEQUENCES - PHANTOM STUDY [J].
KJOS, BO ;
EHMAN, RL ;
BRANTZAWADZKI, M .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1985, 144 (06) :1157-1163
[10]   Examiner repeatability of patellar cartilage T2 values [J].
Koff, Matthew F. ;
Parratte, Sebastien ;
Amrami, Kimberly K. ;
Kaufman, Kenton R. .
MAGNETIC RESONANCE IMAGING, 2009, 27 (01) :131-136