Deliverable navigation for multicriteria step and shoot IMRT treatment planning

被引:22
作者
Craft, David [1 ]
Richter, Christian [1 ]
机构
[1] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
关键词
DIRECT APERTURE OPTIMIZATION; NORMAL CONSTRAINT METHOD; PARETO SURFACES;
D O I
10.1088/0031-9155/58/1/87
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We consider Pareto surface based multi-criteria optimization for step and shoot IMRT planning. By analyzing two navigation algorithms, we show both theoretically and in practice that the number of plans needed to form convex combinations of plans during navigation can be kept small (much less than the theoretical maximum number needed in general, which is equal to the number of objectives for on-surface Pareto navigation). Therefore a workable approach for directly deliverable navigation in this setting is to segment the underlying Pareto surface plans and then enforce the mild restriction that only a small number of these plans are active at any time during plan navigation, thus limiting the total number of segments used in the final plan.
引用
收藏
页码:87 / 103
页数:17
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