Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels

被引：8
|
作者：
Zhang, D. Y. [1 ]
Hu, Z. [1 ]
Lu, S. T. [1 ]
Li, S. D. [1 ]
Yang, Z. M. [2 ]
Li, P. W. [2 ]
机构：
[1] Guangdong Ocean Univ, Sch Chem & Environm Sci, Dept Appl Chem, Zhanjiang 524088, Guangdong, Peoples R China
[2] Chinese Acad Trop Agr Sci, Agr Prod Proc Res Inst, Zhanjiang 524001, Guangdong, Peoples R China
来源：
2ND INTERNATIONAL CONFERENCE ON MATERIAL STRENGTH AND APPLIED MECHANICS | 2019年 / 629卷
关键词：
POLYMER;
D O I：
10.1088/1757-899X/629/1/012038
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with beta-glycerophosphate disodium as a thermosensitizer. The hydrogels were then characterized by FTIR, H-1-NMR, SEM and rheology analysis. The results demonstrated that the thermosensitive hydrogels were prepared at 37 degrees C within several minutes by mixing 2% catechol-functionalized chitosan with 30% beta-glycerophosphate disodium at a ratio of 8:2, and these thermosensitive hydrogels with porous network structure were expected to be developed as biomedical materials with wide applications.
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页数：6
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