Recent advances in dual-emission ratiometric fluorescence probes for chemo/biosensing and bioimaging of biomarkers

被引：447
作者：
Gui, Rijun [1 ]
Jin, Hui [1 ]
Bu, Xiangning [1 ]
Fu, Yongxin [1 ]
Wang, Zonghua [1 ]
Liu, Qingyun [2 ]
机构：
[1] Qingdao Univ, Coll Chem & Chem Engn, Shandong Sino Japanese Ctr Collaborat Res Carbon, Qingdao 266071, Peoples R China
[2] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266590, Peoples R China
来源：
COORDINATION CHEMISTRY REVIEWS | 2019年 / 383卷
基金：
中国国家自然科学基金;
关键词：
Ratiometric fluorescence; Visual detection; Bioimaging; Biosensors; Biomarkers; HIGHLY SELECTIVE DETECTION; PAPER-BASED PLATFORM; QUANTUM DOTS; ANTHRAX BIOMARKER; CARBON DOTS; SENSITIVE DETECTION; ALKALINE-PHOSPHATASE; OXIDATIVE STRESS; ENERGY-TRANSFER; LIVING CELLS;
D O I：
10.1016/j.ccr.2019.01.004
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A biomarker-based detection improves early diagnosis and subsequent treatment of diseases. Chemo/biosensing and bioimaging play a crucial role in biomarker detection. Ratiometric fluorescence (FL) probes provide built-in self-calibration for the correction of various target-independent factors and attract particular attention for analytical sensing and optical imaging. Based on the potential to provide a precise, quantitative, visual and real-time analysis, ratiometric FL probes are widely employed for chemo/biosensing and bioimaging detection of biomarkers. In this review, we systematically summarize the recent progress on dual-emission ratiometric FL probes. First, two general categories of ratiometric FL probes are introduced, involving ratiometric FL with one reference signal and two reversible signal changes. Then, fabrication methods of ratiometric FL probes are summarized in detail, including nanoparticle- or organic dye-embedded probes with dual-emission FL, fluorescent nanoparticles and organic dyes dual-embedded probes. Analytical applications of ratiometric FL probes are described overall, referring to different biomarker types and detection mechanisms, ratiometric FL chemo/biosensing in external samples and FL visual detection, ratiometric FL bioimaging in cells and tissues of small animals. Current states, probable challenges and future perspectives of ratiometric FL probes for biomarker detection are discussed rationally. This comprehensive review is attractive for numerous scientists from different areas, such as material science, chemistry, biomedicine, engineering, physics, etc. This review covers a wide range of scientific disciplines and benefits further development of functionalized optical materials, luminescent devices and bioimaging technique. (C) 2019 Elsevier B.V. All rights reserved.
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页码：82 / 103
页数：22
相关论文
共 130 条
[71]   Naked-eye and ratiometric fluorescence probe for fast and sensitive detection of hydrogen sulfide and its application in bioimaging [J].
Ma, Jianlong ;
Li, Feifei ;
Li, Qiang ;
Li, Yijing ;
Yan, Chaoxian ;
Lu, Xiaofeng ;
Guo, Yong .
NEW JOURNAL OF CHEMISTRY, 2018, 42 (23) :19272-19278
[72]   Simple construction of ratiometric fluorescent probe for the detection of dopamine and tyrosinase by the naked eye [J].
Mao, Guobin ;
Du, Mingyuan ;
Wang, Xinxin ;
Ji, Xinghu ;
He, Zhike .
ANALYST, 2018, 143 (21) :5295-5301
[73]   Compact quantum dot-antibody conjugates for FRET immunoassays with subnanomolar detection limits [J].
Mattera, Lucia ;
Bhuckory, Shashi ;
Wegner, K. David ;
Qiu, Xue ;
Agnese, Fabio ;
Lincheneau, Christophe ;
Senden, Tim ;
Djurado, David ;
Charbonniere, Loic J. ;
Hildebrandt, Niko ;
Reiss, Peter .
NANOSCALE, 2016, 8 (21) :11275-11283
[74]   Two-Photon Absorbing Nanocrystal Sensors for Ratiometric Detection of Oxygen [J].
McLaurin, Emily J. ;
Greytak, Andrew B. ;
Bawendi, Moungi G. ;
Nocera, Daniel G. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (36) :12994-13001
[75]   A dual-colored ratiometric-fluorescent oligonucleotide probe for the detection of human telomerase RNA in cell extracts [J].
Ning, Dianhua ;
He, Changtian ;
Liu, Zhengjie ;
Liu, Cui ;
Wu, Qilong ;
Zhao, TingTing ;
Liu, Renyong .
ANALYST, 2017, 142 (10) :1697-1702
[76]   Ratiometric fluorescence transduction by hybridization after isothermal amplification for determination of zeptomole quantities of oligonucleotide biomarkers with a paper-based platform and camera-based detection [J].
Noor, M. Omair ;
Hrovat, David ;
Moazami-Goudarzi, Maryam ;
Espie, George S. ;
Krull, Ulrich J. .
ANALYTICA CHIMICA ACTA, 2015, 885 :156-165
[77]   Camera-Based Ratiometric Fluorescence Transduction of Nucleic Acid Hybridization with Reagentless Signal Amplification on a Paper-Based Platform Using Immobilized Quantum Dots as Donors [J].
Noor, M. Omair ;
Krull, Ulrich J. .
ANALYTICAL CHEMISTRY, 2014, 86 (20) :10331-10339
[78]   Fluorescent europium-modified polymer nanoparticles for rapid and sensitive anthrax sensors [J].
Oh, Wan-Kyu ;
Jeong, Yoon Seon ;
Song, Jooyoung ;
Jang, Jyongsik .
BIOSENSORS & BIOELECTRONICS, 2011, 29 (01) :172-177
[79]   Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression [J].
Pallaoro, Alessia ;
Braun, Gary B. ;
Moskovits, Martin .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (40) :16559-16564
[80]   Fluorescent nanoprobe for in-vivo ratiometric imaging of endogenous hydrogen peroxide resulted from drug-induced organ damages [J].
Peng, Jin ;
Hou, Xianfeng ;
Zeng, Fang ;
Wu, Shuizhu .
BIOSENSORS & BIOELECTRONICS, 2017, 94 :278-285
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